Antimicrobial and Anti-Inflammatory Activities of MAF-1-Derived Antimicrobial Peptide Mt6 and Its D-Enantiomer D-Mt6 against Acinetobacter baumannii by Targeting Cell Membranes and Lipopolysaccharide Interaction

Antimicrobial and Anti-Inflammatory Activities of MAF-1-Derived Antimicrobial Peptide Mt6 and Its D-Enantiomer D-Mt6 against Acinetobacter baumannii by Targeting Cell Membranes and Lipopolysaccharide Interaction

ABSTRACT Antibiotic resistance in Acinetobacter baumannii is on the rise around the world, highlighting the urgent need for novel antimicrobial drugs. Antimicrobial peptides (AMPs) contribute to effective protection against infections by pathogens, making them the most promising options for next-gen...

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Bibliographic Details
Main Authors: Delong Kong, Xuan Hua, Rui Zhou, Jie Cui, Tao Wang, Fanyun Kong, Hongjuan You, Xiangye Liu, Joseph Adu-Amankwaah, Guo Guo, Kuiyang Zheng, Jianwei Wu, Renxian Tang
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:Microbiology Spectrum
Subjects:
antimicrobial peptides
anti-inflammation
Acinetobacter baumannii
LPS
SEM
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01312-22

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