Inhibition of MAD2L1 Mediates Pulmonary Fibrosis through Impairment of Mitochondrial Function and Induction of Cell Senescence

Inhibition of MAD2L1 Mediates Pulmonary Fibrosis through Impairment of Mitochondrial Function and Induction of Cell Senescence

Idiopathic pulmonary fibrosis (IPF) is a chronic, irreversible, and progressive interstitial lung disease characterized by recurrent alveolar epithelial cell injury, fibroblast hyperproliferation, and cumulative deposition of extracellular matrix leading to alveolar destruction in the lungs. Mitotic...

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Bibliographic Details
Main Authors:	Lan Wang, Ruyan Wan, Xinyu Chen, Xiaoshu Guo, Zhongzheng Li, Weiming Zhao, Peishuo Yan, Guoying Yu
Format:	Article
Language:	English
Published:	Hindawi Limited 2022-01-01
Series:	Canadian Respiratory Journal
Online Access:	http://dx.doi.org/10.1155/2022/9663354

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