Predictors of priapism incidence and recurrence in sickle cell disease patients
Abstract Background Sickle cell disease (SCD) is a prevalent genetic blood disorder with a high global incidence rate. Individuals with SCD experience lifelong complications; one such recurrent complication is priapism. Given the unfavorable prognosis and the limited knowledge of patients regarding...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2023-09-01
|
| Series: | African Journal of Urology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12301-023-00376-0 |
| _version_ | 1797558780164046848 |
|---|---|
| author | Agustin J. Nanda De Niro Gede Wirya Kusuma Duarsa I Wayan Yudiana Nyoman Gede Prayudi Pande Made Wisnu Tirtayasa Kadek Budi Santosa Yudhistira Pradnyan Kloping |
| author_facet | Agustin J. Nanda De Niro Gede Wirya Kusuma Duarsa I Wayan Yudiana Nyoman Gede Prayudi Pande Made Wisnu Tirtayasa Kadek Budi Santosa Yudhistira Pradnyan Kloping |
| author_sort | Agustin J. Nanda De Niro |
| collection | DOAJ |
| description | Abstract Background Sickle cell disease (SCD) is a prevalent genetic blood disorder with a high global incidence rate. Individuals with SCD experience lifelong complications; one such recurrent complication is priapism. Given the unfavorable prognosis and the limited knowledge of patients regarding priapism, healthcare professionals need to identify factors that can aid in diagnosing priapism in SCD patients. Main body of the abstract A comprehensive literature search was conducted using four databases, namely MEDLINE, The Cochrane Library, ScienceDirect, and Google Scholar, following the PRISMA guidelines. The quality and risk of bias assessment were performed using the ROBINS-I tool (Risk Of Bias in Non-Randomized Studies of Interventions) according to guidelines by the Cochrane Collaboration. The literature search yielded a total of 4434 studies, out of which six studies met the eligibility criteria. Short conclusions The findings from the selected studies revealed that advancing age and a higher frequency of priapism episodes were significant predictors of priapism occurrence in SCD patients. These findings underscore the importance of early recognition and management of priapism in this patient population. |
| first_indexed | 2024-03-10T17:36:13Z |
| format | Article |
| id | doaj.art-19fc556c89d34d00a940dcde2fa759bd |
| institution | Directory Open Access Journal |
| issn | 1961-9987 |
| language | English |
| last_indexed | 2024-03-10T17:36:13Z |
| publishDate | 2023-09-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | African Journal of Urology |
| spelling | doaj.art-19fc556c89d34d00a940dcde2fa759bd2023-11-20T09:50:46ZengSpringerOpenAfrican Journal of Urology1961-99872023-09-0129111010.1186/s12301-023-00376-0Predictors of priapism incidence and recurrence in sickle cell disease patientsAgustin J. Nanda De Niro0Gede Wirya Kusuma Duarsa1I Wayan Yudiana2Nyoman Gede Prayudi3Pande Made Wisnu Tirtayasa4Kadek Budi Santosa5Yudhistira Pradnyan Kloping6Urology Surgery Department, Prof. dr. I.G.N.G Ngoerah General HospitalUrology Surgery Department, Prof. dr. I.G.N.G Ngoerah General HospitalUrology Surgery Department, Prof. dr. I.G.N.G Ngoerah General HospitalUrology Surgery Department, Prof. dr. I.G.N.G Ngoerah General HospitalUrology Surgery Department, Prof. dr. I.G.N.G Ngoerah General HospitalUrology Surgery Department, Prof. dr. I.G.N.G Ngoerah General HospitalAirlangga UniversityAbstract Background Sickle cell disease (SCD) is a prevalent genetic blood disorder with a high global incidence rate. Individuals with SCD experience lifelong complications; one such recurrent complication is priapism. Given the unfavorable prognosis and the limited knowledge of patients regarding priapism, healthcare professionals need to identify factors that can aid in diagnosing priapism in SCD patients. Main body of the abstract A comprehensive literature search was conducted using four databases, namely MEDLINE, The Cochrane Library, ScienceDirect, and Google Scholar, following the PRISMA guidelines. The quality and risk of bias assessment were performed using the ROBINS-I tool (Risk Of Bias in Non-Randomized Studies of Interventions) according to guidelines by the Cochrane Collaboration. The literature search yielded a total of 4434 studies, out of which six studies met the eligibility criteria. Short conclusions The findings from the selected studies revealed that advancing age and a higher frequency of priapism episodes were significant predictors of priapism occurrence in SCD patients. These findings underscore the importance of early recognition and management of priapism in this patient population.https://doi.org/10.1186/s12301-023-00376-0PriapismSickle cell diseasePredictors |
| spellingShingle | Agustin J. Nanda De Niro Gede Wirya Kusuma Duarsa I Wayan Yudiana Nyoman Gede Prayudi Pande Made Wisnu Tirtayasa Kadek Budi Santosa Yudhistira Pradnyan Kloping Predictors of priapism incidence and recurrence in sickle cell disease patients African Journal of Urology Priapism Sickle cell disease Predictors |
| title | Predictors of priapism incidence and recurrence in sickle cell disease patients |
| title_full | Predictors of priapism incidence and recurrence in sickle cell disease patients |
| title_fullStr | Predictors of priapism incidence and recurrence in sickle cell disease patients |
| title_full_unstemmed | Predictors of priapism incidence and recurrence in sickle cell disease patients |
| title_short | Predictors of priapism incidence and recurrence in sickle cell disease patients |
| title_sort | predictors of priapism incidence and recurrence in sickle cell disease patients |
| topic | Priapism Sickle cell disease Predictors |
| url | https://doi.org/10.1186/s12301-023-00376-0 |
| work_keys_str_mv | AT agustinjnandadeniro predictorsofpriapismincidenceandrecurrenceinsicklecelldiseasepatients AT gedewiryakusumaduarsa predictorsofpriapismincidenceandrecurrenceinsicklecelldiseasepatients AT iwayanyudiana predictorsofpriapismincidenceandrecurrenceinsicklecelldiseasepatients AT nyomangedeprayudi predictorsofpriapismincidenceandrecurrenceinsicklecelldiseasepatients AT pandemadewisnutirtayasa predictorsofpriapismincidenceandrecurrenceinsicklecelldiseasepatients AT kadekbudisantosa predictorsofpriapismincidenceandrecurrenceinsicklecelldiseasepatients AT yudhistirapradnyankloping predictorsofpriapismincidenceandrecurrenceinsicklecelldiseasepatients |