The impact of lesion side on bilateral upper limb coordination after stroke
Abstract Background A stroke frequently results in impaired performance of activities of daily life. Many of these are highly dependent on effective coordination between the two arms. In the context of bimanual movements, cyclic rhythmical bilateral arm coordination patterns can be classified into t...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-12-01
|
| Series: | Journal of NeuroEngineering and Rehabilitation |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12984-023-01288-4 |
| _version_ | 1797388453856411648 |
|---|---|
| author | Pei-Cheng Shih Christopher J. Steele Dennis Hoepfel Toni Muffel Arno Villringer Bernhard Sehm |
| author_facet | Pei-Cheng Shih Christopher J. Steele Dennis Hoepfel Toni Muffel Arno Villringer Bernhard Sehm |
| author_sort | Pei-Cheng Shih |
| collection | DOAJ |
| description | Abstract Background A stroke frequently results in impaired performance of activities of daily life. Many of these are highly dependent on effective coordination between the two arms. In the context of bimanual movements, cyclic rhythmical bilateral arm coordination patterns can be classified into two fundamental modes: in-phase (bilateral homologous muscles contract simultaneously) and anti-phase (bilateral muscles contract alternately) movements. We aimed to investigate how patients with left (LHS) and right (RHS) hemispheric stroke are differentially affected in both individual-limb control and inter-limb coordination during bilateral movements. Methods We used kinematic measurements to assess bilateral coordination abilities of 18 chronic hemiparetic stroke patients (9 LHS; 9 RHS) and 18 age- and sex-matched controls. Using KINARM upper-limb exoskeleton system, we examined individual-limb control by quantifying trajectory variability in each hand and inter-limb coordination by computing the phase synchronization between hands during anti- and in-phase movements. Results RHS patients exhibited greater impairment in individual- and inter-limb control during anti-phase movements, whilst LHS patients showed greater impairment in individual-limb control during in-phase movements alone. However, LHS patients further showed a swap in hand dominance during in-phase movements. Conclusions The current study used individual-limb and inter-limb kinematic profiles and showed that bilateral movements are differently impaired in patients with left vs. right hemispheric strokes. Our results demonstrate that both fundamental bilateral coordination modes are differently controlled in both hemispheres using a lesion model approach. From a clinical perspective, we suggest that lesion side should be taken into account for more individually targeted bilateral coordination training strategies. Trial registration: the current experiment is not a health care intervention study. |
| first_indexed | 2024-03-08T22:41:02Z |
| format | Article |
| id | doaj.art-19fe70f74b744617911e55354aa267bf |
| institution | Directory Open Access Journal |
| issn | 1743-0003 |
| language | English |
| last_indexed | 2024-03-08T22:41:02Z |
| publishDate | 2023-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of NeuroEngineering and Rehabilitation |
| spelling | doaj.art-19fe70f74b744617911e55354aa267bf2023-12-17T12:09:04ZengBMCJournal of NeuroEngineering and Rehabilitation1743-00032023-12-0120111310.1186/s12984-023-01288-4The impact of lesion side on bilateral upper limb coordination after strokePei-Cheng Shih0Christopher J. Steele1Dennis Hoepfel2Toni Muffel3Arno Villringer4Bernhard Sehm5Department of Neurology, Max Planck Institute for Human Cognitive and Brain SciencesDepartment of Neurology, Max Planck Institute for Human Cognitive and Brain SciencesClinic and Polyclinic for Psychiatry and PsychotherapyDepartment of Neurology, Max Planck Institute for Human Cognitive and Brain SciencesDepartment of Neurology, Max Planck Institute for Human Cognitive and Brain SciencesDepartment of Neurology, Max Planck Institute for Human Cognitive and Brain SciencesAbstract Background A stroke frequently results in impaired performance of activities of daily life. Many of these are highly dependent on effective coordination between the two arms. In the context of bimanual movements, cyclic rhythmical bilateral arm coordination patterns can be classified into two fundamental modes: in-phase (bilateral homologous muscles contract simultaneously) and anti-phase (bilateral muscles contract alternately) movements. We aimed to investigate how patients with left (LHS) and right (RHS) hemispheric stroke are differentially affected in both individual-limb control and inter-limb coordination during bilateral movements. Methods We used kinematic measurements to assess bilateral coordination abilities of 18 chronic hemiparetic stroke patients (9 LHS; 9 RHS) and 18 age- and sex-matched controls. Using KINARM upper-limb exoskeleton system, we examined individual-limb control by quantifying trajectory variability in each hand and inter-limb coordination by computing the phase synchronization between hands during anti- and in-phase movements. Results RHS patients exhibited greater impairment in individual- and inter-limb control during anti-phase movements, whilst LHS patients showed greater impairment in individual-limb control during in-phase movements alone. However, LHS patients further showed a swap in hand dominance during in-phase movements. Conclusions The current study used individual-limb and inter-limb kinematic profiles and showed that bilateral movements are differently impaired in patients with left vs. right hemispheric strokes. Our results demonstrate that both fundamental bilateral coordination modes are differently controlled in both hemispheres using a lesion model approach. From a clinical perspective, we suggest that lesion side should be taken into account for more individually targeted bilateral coordination training strategies. Trial registration: the current experiment is not a health care intervention study.https://doi.org/10.1186/s12984-023-01288-4Upper extremityRehabilitationStrokeMovement kinematicSynchronization |
| spellingShingle | Pei-Cheng Shih Christopher J. Steele Dennis Hoepfel Toni Muffel Arno Villringer Bernhard Sehm The impact of lesion side on bilateral upper limb coordination after stroke Journal of NeuroEngineering and Rehabilitation Upper extremity Rehabilitation Stroke Movement kinematic Synchronization |
| title | The impact of lesion side on bilateral upper limb coordination after stroke |
| title_full | The impact of lesion side on bilateral upper limb coordination after stroke |
| title_fullStr | The impact of lesion side on bilateral upper limb coordination after stroke |
| title_full_unstemmed | The impact of lesion side on bilateral upper limb coordination after stroke |
| title_short | The impact of lesion side on bilateral upper limb coordination after stroke |
| title_sort | impact of lesion side on bilateral upper limb coordination after stroke |
| topic | Upper extremity Rehabilitation Stroke Movement kinematic Synchronization |
| url | https://doi.org/10.1186/s12984-023-01288-4 |
| work_keys_str_mv | AT peichengshih theimpactoflesionsideonbilateralupperlimbcoordinationafterstroke AT christopherjsteele theimpactoflesionsideonbilateralupperlimbcoordinationafterstroke AT dennishoepfel theimpactoflesionsideonbilateralupperlimbcoordinationafterstroke AT tonimuffel theimpactoflesionsideonbilateralupperlimbcoordinationafterstroke AT arnovillringer theimpactoflesionsideonbilateralupperlimbcoordinationafterstroke AT bernhardsehm theimpactoflesionsideonbilateralupperlimbcoordinationafterstroke AT peichengshih impactoflesionsideonbilateralupperlimbcoordinationafterstroke AT christopherjsteele impactoflesionsideonbilateralupperlimbcoordinationafterstroke AT dennishoepfel impactoflesionsideonbilateralupperlimbcoordinationafterstroke AT tonimuffel impactoflesionsideonbilateralupperlimbcoordinationafterstroke AT arnovillringer impactoflesionsideonbilateralupperlimbcoordinationafterstroke AT bernhardsehm impactoflesionsideonbilateralupperlimbcoordinationafterstroke |