The impact on quality of life from informing diagnosis in patients with cancer: a systematic review and meta-analysis
Abstract Background The aim of this study was to assess the impact on quality of life from informing patients with cancer of their diagnosis and disease status. Method We searched the follow databases, PubMed, CENTRAL (Cochrane Central Register of Controlled Trials), PsycINFO, WEB OF SCIENCE, Embase...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-07-01
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| Series: | BMC Cancer |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12885-020-07096-6 |
| _version_ | 1828961886610128896 |
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| author | Miao Wan Xianggui Luo Juan Wang Louis. B Mvogo Ndzana Chen Chang Zhenfen Li Jianglin Zhang |
| author_facet | Miao Wan Xianggui Luo Juan Wang Louis. B Mvogo Ndzana Chen Chang Zhenfen Li Jianglin Zhang |
| author_sort | Miao Wan |
| collection | DOAJ |
| description | Abstract Background The aim of this study was to assess the impact on quality of life from informing patients with cancer of their diagnosis and disease status. Method We searched the follow databases, PubMed, CENTRAL (Cochrane Central Register of Controlled Trials), PsycINFO, WEB OF SCIENCE, Embase, CBM (Chinese Biomedical Literature database), WANFANG database (Chinese Medicine Premier), and CNKI (China National Knowledge Infrastructure), using the following terms: neoplasm, cancer, tumor, tumor, carcinoma, disclosure, truth telling, breaking bad news, knowledge, knowing, awareness, quality of life, QOL. Pairs of reviewers independently screened documents and extracted the data, and the meta-analysis was performed using Revman 5.0 software. Results Eleven thousand seven hundred forty records retrieved from the databases and 23 studies were included in the final analysis. A meta-analysis revealed that there were no differences in either the general quality of life and symptoms of fatigue, pain, dyspnea, insomnia, appetite loss, and diarrhea, between informed and uniformed cancer patients (P > 0.05). There were also no differences found between the patient groups in physical function, role function, cognitive activity, and emotional function (P > 0.05). In terms of vitality, patients who were completely informed about their diagnosis showed higher vitality than uniformed patients. Uninformed patients seemed to have lower social function scores. Between partly informed and uninformed cancer patients, no differences were found in their general quality of life, function domains, and disease-related symptoms (P > 0.05). Conclusion Informing cancer patients of their diagnosis may not have a detrimental effect on their quality of life. Trial registration CRD42017060073 . |
| first_indexed | 2024-12-14T09:54:01Z |
| format | Article |
| id | doaj.art-19ff25500c8f4a4fb38b3ddcc2f5bd11 |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-12-14T09:54:01Z |
| publishDate | 2020-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-19ff25500c8f4a4fb38b3ddcc2f5bd112022-12-21T23:07:26ZengBMCBMC Cancer1471-24072020-07-0120111310.1186/s12885-020-07096-6The impact on quality of life from informing diagnosis in patients with cancer: a systematic review and meta-analysisMiao Wan0Xianggui Luo1Juan Wang2Louis. B Mvogo Ndzana3Chen Chang4Zhenfen Li5Jianglin Zhang6Dermatology Department of Xiangya Hospital, Central SouthUniversityDermatology Department of Xiangya Hospital, Central SouthUniversityMaternity Department of Xiangya Hospital, Central South UniversityDermatology Department of Xiangya Hospital, Central SouthUniversityThe Second Clinical Medical College of Lanzhou UniversityThe Second Clinical Medical College of Lanzhou UniversityDermatology Department of Xiangya Hospital, Central SouthUniversityAbstract Background The aim of this study was to assess the impact on quality of life from informing patients with cancer of their diagnosis and disease status. Method We searched the follow databases, PubMed, CENTRAL (Cochrane Central Register of Controlled Trials), PsycINFO, WEB OF SCIENCE, Embase, CBM (Chinese Biomedical Literature database), WANFANG database (Chinese Medicine Premier), and CNKI (China National Knowledge Infrastructure), using the following terms: neoplasm, cancer, tumor, tumor, carcinoma, disclosure, truth telling, breaking bad news, knowledge, knowing, awareness, quality of life, QOL. Pairs of reviewers independently screened documents and extracted the data, and the meta-analysis was performed using Revman 5.0 software. Results Eleven thousand seven hundred forty records retrieved from the databases and 23 studies were included in the final analysis. A meta-analysis revealed that there were no differences in either the general quality of life and symptoms of fatigue, pain, dyspnea, insomnia, appetite loss, and diarrhea, between informed and uniformed cancer patients (P > 0.05). There were also no differences found between the patient groups in physical function, role function, cognitive activity, and emotional function (P > 0.05). In terms of vitality, patients who were completely informed about their diagnosis showed higher vitality than uniformed patients. Uninformed patients seemed to have lower social function scores. Between partly informed and uninformed cancer patients, no differences were found in their general quality of life, function domains, and disease-related symptoms (P > 0.05). Conclusion Informing cancer patients of their diagnosis may not have a detrimental effect on their quality of life. Trial registration CRD42017060073 .http://link.springer.com/article/10.1186/s12885-020-07096-6Diagnosis awarenessCancerDiagnosis disclosureMeta-analysisQuality of lifeSystematic review |
| spellingShingle | Miao Wan Xianggui Luo Juan Wang Louis. B Mvogo Ndzana Chen Chang Zhenfen Li Jianglin Zhang The impact on quality of life from informing diagnosis in patients with cancer: a systematic review and meta-analysis BMC Cancer Diagnosis awareness Cancer Diagnosis disclosure Meta-analysis Quality of life Systematic review |
| title | The impact on quality of life from informing diagnosis in patients with cancer: a systematic review and meta-analysis |
| title_full | The impact on quality of life from informing diagnosis in patients with cancer: a systematic review and meta-analysis |
| title_fullStr | The impact on quality of life from informing diagnosis in patients with cancer: a systematic review and meta-analysis |
| title_full_unstemmed | The impact on quality of life from informing diagnosis in patients with cancer: a systematic review and meta-analysis |
| title_short | The impact on quality of life from informing diagnosis in patients with cancer: a systematic review and meta-analysis |
| title_sort | impact on quality of life from informing diagnosis in patients with cancer a systematic review and meta analysis |
| topic | Diagnosis awareness Cancer Diagnosis disclosure Meta-analysis Quality of life Systematic review |
| url | http://link.springer.com/article/10.1186/s12885-020-07096-6 |
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