Characterization of diffusing sub-10 nm nano-objects using single anti-resonant element optical fibers

Abstract Accurate characterization of diffusing nanoscale species is increasingly important for revealing processes at the nanoscale, with fiber-assisted nanoparticle-tracking-analysis representing a new and promising approach in this field. In this work, we uncover the potential of this approach fo...

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Main Authors: Torsten Wieduwilt, Ronny Förster, Mona Nissen, Jens Kobelke, Markus A. Schmidt
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39021-3
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author Torsten Wieduwilt
Ronny Förster
Mona Nissen
Jens Kobelke
Markus A. Schmidt
author_facet Torsten Wieduwilt
Ronny Förster
Mona Nissen
Jens Kobelke
Markus A. Schmidt
author_sort Torsten Wieduwilt
collection DOAJ
description Abstract Accurate characterization of diffusing nanoscale species is increasingly important for revealing processes at the nanoscale, with fiber-assisted nanoparticle-tracking-analysis representing a new and promising approach in this field. In this work, we uncover the potential of this approach for the characterization of very small nanoparticles (<20 nm) through experimental studies, statistical analysis and the employment of a sophisticated fiber and chip design. The central results is the characterization of diffusing nanoparticles as small as 9 nm with record-high precision, corresponding to the smallest diameter yet determined for an individual nanoparticle with nanoparticle-tracking-analysis using elastic light scattering alone. Here, the detectable scattering cross-section is limited only by the background scattering of the ultrapure water, thus reaching the fundamental limit of Nanoparticle-Tracking-Analysis in general. The obtained results outperform other realizations and allow access to previously difficult to address application fields such as understanding nanoparticle growth or control of pharmaceuticals.
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spelling doaj.art-1a0505adb9c44f59b8fcc7a312afc6902023-06-11T11:19:49ZengNature PortfolioNature Communications2041-17232023-06-011411710.1038/s41467-023-39021-3Characterization of diffusing sub-10 nm nano-objects using single anti-resonant element optical fibersTorsten Wieduwilt0Ronny Förster1Mona Nissen2Jens Kobelke3Markus A. Schmidt4Leibniz Institute of Photonic TechnologyLeibniz Institute of Photonic TechnologyLeibniz Institute of Photonic TechnologyLeibniz Institute of Photonic TechnologyLeibniz Institute of Photonic TechnologyAbstract Accurate characterization of diffusing nanoscale species is increasingly important for revealing processes at the nanoscale, with fiber-assisted nanoparticle-tracking-analysis representing a new and promising approach in this field. In this work, we uncover the potential of this approach for the characterization of very small nanoparticles (<20 nm) through experimental studies, statistical analysis and the employment of a sophisticated fiber and chip design. The central results is the characterization of diffusing nanoparticles as small as 9 nm with record-high precision, corresponding to the smallest diameter yet determined for an individual nanoparticle with nanoparticle-tracking-analysis using elastic light scattering alone. Here, the detectable scattering cross-section is limited only by the background scattering of the ultrapure water, thus reaching the fundamental limit of Nanoparticle-Tracking-Analysis in general. The obtained results outperform other realizations and allow access to previously difficult to address application fields such as understanding nanoparticle growth or control of pharmaceuticals.https://doi.org/10.1038/s41467-023-39021-3
spellingShingle Torsten Wieduwilt
Ronny Förster
Mona Nissen
Jens Kobelke
Markus A. Schmidt
Characterization of diffusing sub-10 nm nano-objects using single anti-resonant element optical fibers
Nature Communications
title Characterization of diffusing sub-10 nm nano-objects using single anti-resonant element optical fibers
title_full Characterization of diffusing sub-10 nm nano-objects using single anti-resonant element optical fibers
title_fullStr Characterization of diffusing sub-10 nm nano-objects using single anti-resonant element optical fibers
title_full_unstemmed Characterization of diffusing sub-10 nm nano-objects using single anti-resonant element optical fibers
title_short Characterization of diffusing sub-10 nm nano-objects using single anti-resonant element optical fibers
title_sort characterization of diffusing sub 10 nm nano objects using single anti resonant element optical fibers
url https://doi.org/10.1038/s41467-023-39021-3
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