| Summary: | <i>Mycobacterium uberis</i> (<i>M. uberis</i>) is a recently described non-tuberculous mycobacterium phylogenetically close to <i>Mycobacterium leprae</i> (<i>M. leprae</i>) and <i>Mycobacterium lepromatosis</i> (<i>M. lepromatosis</i>). This pathogen classically causes nodular thelitis in cattle and goats. Here, we discuss what seems to be the first described case of <i>M. uberis</i> infection in a novel anatomical site, in the proximal or distal position (information not available) of the radius/ulna area of a cow. As this case was discovered in the framework of bovine tuberculosis (bTB) surveillance program in France, this type of infection could interfere with the screening and diagnostic tools employed for bTB.
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