Long Non-Coding RNAs in the Control of Gametogenesis: Lessons from Fission Yeast
Long non-coding RNAs (lncRNAs) contribute to cell fate decisions by modulating genome expression and stability. In the fission yeast <i>Schizosaccharomyces pombe</i>, the transition from mitosis to meiosis results in a marked remodeling of gene expression profiles, which ultimately ensur...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Non-Coding RNA |
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| Online Access: | https://www.mdpi.com/2311-553X/7/2/34 |
| _version_ | 1797530508472614912 |
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| author | Vedrana Andric Mathieu Rougemaille |
| author_facet | Vedrana Andric Mathieu Rougemaille |
| author_sort | Vedrana Andric |
| collection | DOAJ |
| description | Long non-coding RNAs (lncRNAs) contribute to cell fate decisions by modulating genome expression and stability. In the fission yeast <i>Schizosaccharomyces pombe</i>, the transition from mitosis to meiosis results in a marked remodeling of gene expression profiles, which ultimately ensures gamete production and inheritance of genetic information to the offspring. This key developmental process involves a set of dedicated lncRNAs that shape cell cycle-dependent transcriptomes through a variety of mechanisms, including epigenetic modifications and the modulation of transcription, post-transcriptional and post-translational regulations, and that contribute to meiosis-specific chromosomal events. In this review, we summarize the biology of these lncRNAs, from their identification to mechanism of action, and discuss their regulatory role in the control of gametogenesis. |
| first_indexed | 2024-03-10T10:29:59Z |
| format | Article |
| id | doaj.art-1a080f961ca84b13be89a2e80ae91a00 |
| institution | Directory Open Access Journal |
| issn | 2311-553X |
| language | English |
| last_indexed | 2024-03-10T10:29:59Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Non-Coding RNA |
| spelling | doaj.art-1a080f961ca84b13be89a2e80ae91a002023-11-21T23:41:45ZengMDPI AGNon-Coding RNA2311-553X2021-06-01723410.3390/ncrna7020034Long Non-Coding RNAs in the Control of Gametogenesis: Lessons from Fission YeastVedrana Andric0Mathieu Rougemaille1Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, 91198 Gif-sur-Yvette, FranceInstitute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, 91198 Gif-sur-Yvette, FranceLong non-coding RNAs (lncRNAs) contribute to cell fate decisions by modulating genome expression and stability. In the fission yeast <i>Schizosaccharomyces pombe</i>, the transition from mitosis to meiosis results in a marked remodeling of gene expression profiles, which ultimately ensures gamete production and inheritance of genetic information to the offspring. This key developmental process involves a set of dedicated lncRNAs that shape cell cycle-dependent transcriptomes through a variety of mechanisms, including epigenetic modifications and the modulation of transcription, post-transcriptional and post-translational regulations, and that contribute to meiosis-specific chromosomal events. In this review, we summarize the biology of these lncRNAs, from their identification to mechanism of action, and discuss their regulatory role in the control of gametogenesis.https://www.mdpi.com/2311-553X/7/2/34fission yeastgametogenesisgene expressionlong non-coding RNAsmitosis to meiosis transition |
| spellingShingle | Vedrana Andric Mathieu Rougemaille Long Non-Coding RNAs in the Control of Gametogenesis: Lessons from Fission Yeast Non-Coding RNA fission yeast gametogenesis gene expression long non-coding RNAs mitosis to meiosis transition |
| title | Long Non-Coding RNAs in the Control of Gametogenesis: Lessons from Fission Yeast |
| title_full | Long Non-Coding RNAs in the Control of Gametogenesis: Lessons from Fission Yeast |
| title_fullStr | Long Non-Coding RNAs in the Control of Gametogenesis: Lessons from Fission Yeast |
| title_full_unstemmed | Long Non-Coding RNAs in the Control of Gametogenesis: Lessons from Fission Yeast |
| title_short | Long Non-Coding RNAs in the Control of Gametogenesis: Lessons from Fission Yeast |
| title_sort | long non coding rnas in the control of gametogenesis lessons from fission yeast |
| topic | fission yeast gametogenesis gene expression long non-coding RNAs mitosis to meiosis transition |
| url | https://www.mdpi.com/2311-553X/7/2/34 |
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