Male histone deacetylase 6 (HDAC6) knockout mice have enhanced ventilatory responses to hypoxic challenge

Male histone deacetylase 6 (HDAC6) knockout mice have enhanced ventilatory responses to hypoxic challenge

Histone deacetylase 6 (HDAC6) is a class II histone deacetylase that is predominantly localized in the cytoplasm of cells. HDAC6 associates with microtubules and regulates acetylation of tubulin and other proteins. The possibility that HDAC6 participates in hypoxic signaling is supported by evidence...

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Bibliographic Details
Main Authors:	Paulina M. Getsy, Gregory A. Coffee, Thomas J. Kelley, Stephen J. Lewis
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-02-01
Series:	Frontiers in Physiology
Subjects:	hypoxia histone deacetylase 6 (HDAC6) mice HIF-1α whole body plesthysmography
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2023.1332810/full

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