Basic and clinical research advances in ischemic stroke
Stroke is the most common cerebrovascular disease worldwide, which seriously affects life quality of survivals and results in huge economic burden of families and society. In terms of clinical treatment for ischemic stroke, apart from thrombolytic therapy with recombinant tissue-type plasminogen act...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tianjin Huanhu Hospital
2018-01-01
|
| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/1715 |
| _version_ | 1811287986794397696 |
|---|---|
| author | Yuan-yuan MA Guo-yuan YANG |
| author_facet | Yuan-yuan MA Guo-yuan YANG |
| author_sort | Yuan-yuan MA |
| collection | DOAJ |
| description | Stroke is the most common cerebrovascular disease worldwide, which seriously affects life quality of survivals and results in huge economic burden of families and society. In terms of clinical treatment for ischemic stroke, apart from thrombolytic therapy with recombinant tissue-type plasminogen activator (rt-PA), the occurrence and successful application of endovascular thrombectomy in patients of ischemic stroke is a major breakthrough. Meanwhile, many novel clinical drugs for ischemic stroke therapy have entered into clinical trials. Most of basic and clinical researches have showed promising results in ischemic stroke therapy. This review mainly summarizes the progress of research during the period of Twelfth Five-Year Plan for National Economic and Social Development on treatment of ischemic stroke, including omics technologies, gene therapy, microRNA (miRNA) interference and stem cell therapy. Stem cell therapy has shown great potential since many clinical trials have been completed or are ongoing. The development and mutual transformation of basic and clinical research will provide valuable and comprehensive information for the precise treatment of ischemic stroke. |
| first_indexed | 2024-04-13T03:29:08Z |
| format | Article |
| id | doaj.art-1a0afeb14df6428fa1f5b136d98af841 |
| institution | Directory Open Access Journal |
| issn | 1672-6731 |
| language | English |
| last_indexed | 2024-04-13T03:29:08Z |
| publishDate | 2018-01-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj.art-1a0afeb14df6428fa1f5b136d98af8412022-12-22T03:04:33ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312018-01-011817181675Basic and clinical research advances in ischemic strokeYuan-yuan MA0Guo-yuan YANG1Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, ChinaDepartment of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China; Neuroscience and Neuroengineering Research Center, Med - X Research Institute and School of Biomedical Engineering, Shanghai Jiaotong University School of Medicine, Shanghai 200030, ChinaStroke is the most common cerebrovascular disease worldwide, which seriously affects life quality of survivals and results in huge economic burden of families and society. In terms of clinical treatment for ischemic stroke, apart from thrombolytic therapy with recombinant tissue-type plasminogen activator (rt-PA), the occurrence and successful application of endovascular thrombectomy in patients of ischemic stroke is a major breakthrough. Meanwhile, many novel clinical drugs for ischemic stroke therapy have entered into clinical trials. Most of basic and clinical researches have showed promising results in ischemic stroke therapy. This review mainly summarizes the progress of research during the period of Twelfth Five-Year Plan for National Economic and Social Development on treatment of ischemic stroke, including omics technologies, gene therapy, microRNA (miRNA) interference and stem cell therapy. Stem cell therapy has shown great potential since many clinical trials have been completed or are ongoing. The development and mutual transformation of basic and clinical research will provide valuable and comprehensive information for the precise treatment of ischemic stroke.http://www.cjcnn.org/index.php/cjcnn/article/view/1715StrokeBrain ischemiaChinaReview |
| spellingShingle | Yuan-yuan MA Guo-yuan YANG Basic and clinical research advances in ischemic stroke Chinese Journal of Contemporary Neurology and Neurosurgery Stroke Brain ischemia China Review |
| title | Basic and clinical research advances in ischemic stroke |
| title_full | Basic and clinical research advances in ischemic stroke |
| title_fullStr | Basic and clinical research advances in ischemic stroke |
| title_full_unstemmed | Basic and clinical research advances in ischemic stroke |
| title_short | Basic and clinical research advances in ischemic stroke |
| title_sort | basic and clinical research advances in ischemic stroke |
| topic | Stroke Brain ischemia China Review |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/1715 |
| work_keys_str_mv | AT yuanyuanma basicandclinicalresearchadvancesinischemicstroke AT guoyuanyang basicandclinicalresearchadvancesinischemicstroke |