Progress in application of terahertz time-domain spectroscopy for pharmaceutical analyses

Terahertz time-domain spectroscopy is an analytical method using terahertz time-domain pulses to study the physical and chemical properties of substances. It has strong potential for application in pharmaceutical analyses as an original non-destructive, efficient and convenient technology for spectr...

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Main Authors: Shuteng Huang, Hanxiu Deng, Xia Wei, Jiayu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1219042/full
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author Shuteng Huang
Hanxiu Deng
Xia Wei
Jiayu Zhang
author_facet Shuteng Huang
Hanxiu Deng
Xia Wei
Jiayu Zhang
author_sort Shuteng Huang
collection DOAJ
description Terahertz time-domain spectroscopy is an analytical method using terahertz time-domain pulses to study the physical and chemical properties of substances. It has strong potential for application in pharmaceutical analyses as an original non-destructive, efficient and convenient technology for spectral detection. This review briefly introduces the working principle of terahertz time-domain spectroscopy technology, focuses on the research achievements of this technology in analyses of chemical drugs, traditional Chinese medicine and biological drugs in the past decade. We also reveal the scientific feasibility of practical application of terahertz time-domain spectroscopy for pharmaceutical detection. Finally, we discuss the problems in practical application of terahertz time-domain spectroscopy technology, and the prospect of further development of this technology in pharmaceutical analyses. We hope that this review can provide a reference for application of terahertz time-domain spectroscopy technology in pharmaceutical analyses in the future.
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spelling doaj.art-1a0d75a1f9b74a26ab56502789a08b7f2023-07-18T10:41:47ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852023-07-011110.3389/fbioe.2023.12190421219042Progress in application of terahertz time-domain spectroscopy for pharmaceutical analysesShuteng Huang0Hanxiu Deng1Xia Wei2Jiayu Zhang3School of Pharmacy, Binzhou Medical University, Yantai, ChinaSchool of Pharmacy, Binzhou Medical University, Yantai, ChinaShandong Institute for Food and Drug Control, Jinan, ChinaSchool of Pharmacy, Binzhou Medical University, Yantai, ChinaTerahertz time-domain spectroscopy is an analytical method using terahertz time-domain pulses to study the physical and chemical properties of substances. It has strong potential for application in pharmaceutical analyses as an original non-destructive, efficient and convenient technology for spectral detection. This review briefly introduces the working principle of terahertz time-domain spectroscopy technology, focuses on the research achievements of this technology in analyses of chemical drugs, traditional Chinese medicine and biological drugs in the past decade. We also reveal the scientific feasibility of practical application of terahertz time-domain spectroscopy for pharmaceutical detection. Finally, we discuss the problems in practical application of terahertz time-domain spectroscopy technology, and the prospect of further development of this technology in pharmaceutical analyses. We hope that this review can provide a reference for application of terahertz time-domain spectroscopy technology in pharmaceutical analyses in the future.https://www.frontiersin.org/articles/10.3389/fbioe.2023.1219042/fullterahertz time-domain spectroscopypharmaceutical analysischemical drugstraditional Chinese medicinebiological drugsprogress in application
spellingShingle Shuteng Huang
Hanxiu Deng
Xia Wei
Jiayu Zhang
Progress in application of terahertz time-domain spectroscopy for pharmaceutical analyses
Frontiers in Bioengineering and Biotechnology
terahertz time-domain spectroscopy
pharmaceutical analysis
chemical drugs
traditional Chinese medicine
biological drugs
progress in application
title Progress in application of terahertz time-domain spectroscopy for pharmaceutical analyses
title_full Progress in application of terahertz time-domain spectroscopy for pharmaceutical analyses
title_fullStr Progress in application of terahertz time-domain spectroscopy for pharmaceutical analyses
title_full_unstemmed Progress in application of terahertz time-domain spectroscopy for pharmaceutical analyses
title_short Progress in application of terahertz time-domain spectroscopy for pharmaceutical analyses
title_sort progress in application of terahertz time domain spectroscopy for pharmaceutical analyses
topic terahertz time-domain spectroscopy
pharmaceutical analysis
chemical drugs
traditional Chinese medicine
biological drugs
progress in application
url https://www.frontiersin.org/articles/10.3389/fbioe.2023.1219042/full
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AT xiawei progressinapplicationofterahertztimedomainspectroscopyforpharmaceuticalanalyses
AT jiayuzhang progressinapplicationofterahertztimedomainspectroscopyforpharmaceuticalanalyses