Anti-psoriatic effects of Honokiol through the inhibition of NF-κB and VEGFR-2 in animal model of K14-VEGF transgenic mouse

Anti-psoriatic effects of Honokiol through the inhibition of NF-κB and VEGFR-2 in animal model of K14-VEGF transgenic mouse

Honokiol (HK), a biphenolic neolignan isolated from Magnolia officinalis, has been reported to possess anti-inflammatory and anti-angiogenic activaties. In this study, our aim was to investigate anti-psoriatic activities of HK and the involved mechanisms. In vitro, the effects of HK on the regulatio...

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Bibliographic Details
Main Authors: Jiaolin Wen, Xianhuo Wang, Heying Pei, Caifeng Xie, Neng Qiu, Shucai Li, Wenwen Wang, Xia Cheng, Lijuan Chen
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Journal of Pharmacological Sciences
Subjects:
Honokiol
Psoriasis
K14-VEGF
NF-κB
VEGFR-2
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861315001061

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