X-ray induced acoustic computed tomography

X-ray imaging has proved invaluable in medical diagnoses and non-destructive testing (NDT) in the past century. However, there remain two major limitations: radiation harm and inaccessibility to the sample. A recent imaging modality, X-ray induced acoustic computed tomography (XACT), allows a novel...

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Main Authors: P. Samant, L. Trevisi, X. Ji, L. Xiang
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Photoacoustics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213597920300173
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author P. Samant
L. Trevisi
X. Ji
L. Xiang
author_facet P. Samant
L. Trevisi
X. Ji
L. Xiang
author_sort P. Samant
collection DOAJ
description X-ray imaging has proved invaluable in medical diagnoses and non-destructive testing (NDT) in the past century. However, there remain two major limitations: radiation harm and inaccessibility to the sample. A recent imaging modality, X-ray induced acoustic computed tomography (XACT), allows a novel solution. In XACT, x-ray induced excitation causes localized heating (<mK) and thermoelastic expansion. This induces a detectable ultrasonic emission, thereby enabling imaging. XACT has the potential to enable low-dose, fast, 3D imaging requiring only single side access. We discuss the fundamentals of XACT and summarize milestones in its evolution over the past several years since its first demonstration using a Medical Linear Accelerator. We highlight XACT’s potential applications in biomedical imaging and NDT, and discuss the latest advanced concepts and future directions.
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spelling doaj.art-1a1602c9364a481ba5784e2609ac2c812022-12-21T19:17:23ZengElsevierPhotoacoustics2213-59792020-09-0119100177X-ray induced acoustic computed tomographyP. Samant0L. Trevisi1X. Ji2L. Xiang3Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, 73071, USA; Department of Oncology, University of Oxford, Oxford, OX3 7DQ, UKChemical, Biological, &amp; Materials Engineering, University of Oklahoma, Norman, 73071, USASchool of Electromechanical Engineering, Guangdong University of Technology, Guangzhou, 510006, Guangdong, ChinaElectrical and Computer Engineering, University of Oklahoma, Norman, 73071, USA; Corresponding author at: 101 David L Boren Blvd Room 2022, Norman, 73071, USA.X-ray imaging has proved invaluable in medical diagnoses and non-destructive testing (NDT) in the past century. However, there remain two major limitations: radiation harm and inaccessibility to the sample. A recent imaging modality, X-ray induced acoustic computed tomography (XACT), allows a novel solution. In XACT, x-ray induced excitation causes localized heating (<mK) and thermoelastic expansion. This induces a detectable ultrasonic emission, thereby enabling imaging. XACT has the potential to enable low-dose, fast, 3D imaging requiring only single side access. We discuss the fundamentals of XACT and summarize milestones in its evolution over the past several years since its first demonstration using a Medical Linear Accelerator. We highlight XACT’s potential applications in biomedical imaging and NDT, and discuss the latest advanced concepts and future directions.http://www.sciencedirect.com/science/article/pii/S2213597920300173X-ray induced acoustic computed tomographyRadiation dosimetryLow dose CTImage guided therapyNon-destructive testingDensity measurement
spellingShingle P. Samant
L. Trevisi
X. Ji
L. Xiang
X-ray induced acoustic computed tomography
Photoacoustics
X-ray induced acoustic computed tomography
Radiation dosimetry
Low dose CT
Image guided therapy
Non-destructive testing
Density measurement
title X-ray induced acoustic computed tomography
title_full X-ray induced acoustic computed tomography
title_fullStr X-ray induced acoustic computed tomography
title_full_unstemmed X-ray induced acoustic computed tomography
title_short X-ray induced acoustic computed tomography
title_sort x ray induced acoustic computed tomography
topic X-ray induced acoustic computed tomography
Radiation dosimetry
Low dose CT
Image guided therapy
Non-destructive testing
Density measurement
url http://www.sciencedirect.com/science/article/pii/S2213597920300173
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