Nostril mass caused by Leishmania spp. in a dog
Canine leishmaniasis (CanL) is a systemic zoonotic disease caused by the protozoan Leishmania, an intracellular macrophage parasite, transmitted by the bite of phlebotomine sandflies. In dogs, the clinical disease is mostly characterised by symptoms associated with viscerocutaneous lesions such as l...
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| Format: | Article |
| Language: | English |
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Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale
2019-01-01
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| Series: | Veterinaria Italiana |
| Online Access: | https://www.veterinariaitaliana.izs.it/index.php/VetIt/article/view/1460 |
| _version_ | 1818877472363511808 |
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| author | Manuela Gizzarelli Valentina Foglia Manzillo Eleonora Fiorentino Aldo Scalone Gaetano Oliva |
| author_facet | Manuela Gizzarelli Valentina Foglia Manzillo Eleonora Fiorentino Aldo Scalone Gaetano Oliva |
| author_sort | Manuela Gizzarelli |
| collection | DOAJ |
| description | Canine leishmaniasis (CanL) is a systemic zoonotic disease caused by the protozoan Leishmania, an intracellular macrophage parasite, transmitted by the bite of phlebotomine sandflies. In dogs, the clinical disease is mostly characterised by symptoms associated with viscerocutaneous lesions such as lymphadenopathy, splenomegaly, skin lesions, and renal and ocular disease caused by the deposition of immune complexes. The parasite may provoke mucosal lesions which cause atypical clinical signs. The aim of this study is to describe an atypical nostril mass in a dog infected by Leishmania. Clinical examination did not show any systemic clinical signs, while haematological, biochemical, and urinary parameters demonstrated a mild disease stage. Diagnosis was confirmed through the isolation of cultured live parasites by biopsy. The dog was treated with a combination of miltefosine and allopurinol, showing full remission of clinical symptoms after 2 months. The authors outline the importance of considering CanL in the differential diagnosis of mucous and tumour-like lesions. |
| first_indexed | 2024-12-19T13:58:50Z |
| format | Article |
| id | doaj.art-1a17adfe056d496389510b19aa4ed1a0 |
| institution | Directory Open Access Journal |
| issn | 0505-401X 1828-1427 |
| language | English |
| last_indexed | 2024-12-19T13:58:50Z |
| publishDate | 2019-01-01 |
| publisher | Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale |
| record_format | Article |
| series | Veterinaria Italiana |
| spelling | doaj.art-1a17adfe056d496389510b19aa4ed1a02022-12-21T20:18:31ZengIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. CaporaleVeterinaria Italiana0505-401X1828-14272019-01-0154310.12834/VetIt.1460.7898.1Nostril mass caused by Leishmania spp. in a dogManuela Gizzarelli0Valentina Foglia Manzillo1Eleonora Fiorentino2Aldo Scalone3Gaetano Oliva4Department of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Napoli, Italy.Department of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Napoli, Italy.Unit of Vector-borne Diseases and International Health, MIPI Department, Istituto Superiore di Sanità, Rome, ItalyUnit of Vector-borne Diseases and International Health, MIPI Department, Istituto Superiore di Sanità, RomeDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Napoli, Italy.Canine leishmaniasis (CanL) is a systemic zoonotic disease caused by the protozoan Leishmania, an intracellular macrophage parasite, transmitted by the bite of phlebotomine sandflies. In dogs, the clinical disease is mostly characterised by symptoms associated with viscerocutaneous lesions such as lymphadenopathy, splenomegaly, skin lesions, and renal and ocular disease caused by the deposition of immune complexes. The parasite may provoke mucosal lesions which cause atypical clinical signs. The aim of this study is to describe an atypical nostril mass in a dog infected by Leishmania. Clinical examination did not show any systemic clinical signs, while haematological, biochemical, and urinary parameters demonstrated a mild disease stage. Diagnosis was confirmed through the isolation of cultured live parasites by biopsy. The dog was treated with a combination of miltefosine and allopurinol, showing full remission of clinical symptoms after 2 months. The authors outline the importance of considering CanL in the differential diagnosis of mucous and tumour-like lesions.https://www.veterinariaitaliana.izs.it/index.php/VetIt/article/view/1460 |
| spellingShingle | Manuela Gizzarelli Valentina Foglia Manzillo Eleonora Fiorentino Aldo Scalone Gaetano Oliva Nostril mass caused by Leishmania spp. in a dog Veterinaria Italiana |
| title | Nostril mass caused by Leishmania spp. in a dog |
| title_full | Nostril mass caused by Leishmania spp. in a dog |
| title_fullStr | Nostril mass caused by Leishmania spp. in a dog |
| title_full_unstemmed | Nostril mass caused by Leishmania spp. in a dog |
| title_short | Nostril mass caused by Leishmania spp. in a dog |
| title_sort | nostril mass caused by leishmania spp in a dog |
| url | https://www.veterinariaitaliana.izs.it/index.php/VetIt/article/view/1460 |
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