THE VALIDITY OF THE HAMILTON DEPRESSION RATING SCALE AS A SCREENING AND DIAGNOSTIC INSTRUMENT FOR DEPRESSION IN PATIENTS WITH EPILEPSY
Aim: To evaluate the concurrent validity of the Hamilton Depression Rating Scale (HAMD-17) against ICD-10 criteria for depressive disorder and its performance as a screening and diagnostic tool for depression in patients with epilepsy (PWE).Subjects and Methods: One hundred and six PWE underwent cli...
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| Format: | Article |
| Language: | English |
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Peytchinski Publishing
2012-10-01
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| Series: | Journal of IMAB |
| Subjects: | |
| Online Access: | http://www.journal-imab-bg.org/issue-2012/book3/JofIMAB2012vol18b3p305-307.pdf |
| _version_ | 1811203953560387584 |
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| author | Koraliya S. Todorova Valentina S. Velikova |
| author_facet | Koraliya S. Todorova Valentina S. Velikova |
| author_sort | Koraliya S. Todorova |
| collection | DOAJ |
| description | Aim: To evaluate the concurrent validity of the Hamilton Depression Rating Scale (HAMD-17) against ICD-10 criteria for depressive disorder and its performance as a screening and diagnostic tool for depression in patients with epilepsy (PWE).Subjects and Methods: One hundred and six PWE underwent clinical psychiatric examination followed by evaluation on HAMD-17. ICD-10 criteria for comorbid depressive disorder were applied. Internal consistency was assessed using Cronbach’s α. A “receiver operating characteristics” (ROC) curve was obtained and the sensitivity, specificity, positive and negative predictive values (PPV, NPV) were calculated for different cut-off points of the HAMD-17.Results: Internal consistency measured by Cronbach’s α was 0.74. Maximal discrimination between depressed and non depressed was obtained at a cut-off score of 8/9 (sensitivity 0.93, specificity 0.98). High sensitivity and NPV at the same cut-off score (sensitivity 0.93, NPV 1.0) show the screening properties, and high specificity and PPV at cut-offs 9/10, the diagnostic properties of the instrument. The area under the ROC curve (AUC=0.746) indicates the concurrent validity of the HAMD-17 score with the ICD-10 criteria for depressive disorder.Conclusion: The validity of the HAMD-17 against ICD-10 criteria for depressive disorder in PWE in our study is fair. The concurrent administration of diagnostic criteria can ascertain the presence of core symptoms of depression. |
| first_indexed | 2024-04-12T03:03:35Z |
| format | Article |
| id | doaj.art-1a1d0ebbc9c14992b229338fac0104c9 |
| institution | Directory Open Access Journal |
| issn | 1312-773X |
| language | English |
| last_indexed | 2024-04-12T03:03:35Z |
| publishDate | 2012-10-01 |
| publisher | Peytchinski Publishing |
| record_format | Article |
| series | Journal of IMAB |
| spelling | doaj.art-1a1d0ebbc9c14992b229338fac0104c92022-12-22T03:50:33ZengPeytchinski PublishingJournal of IMAB1312-773X2012-10-01183305307THE VALIDITY OF THE HAMILTON DEPRESSION RATING SCALE AS A SCREENING AND DIAGNOSTIC INSTRUMENT FOR DEPRESSION IN PATIENTS WITH EPILEPSYKoraliya S. TodorovaValentina S. VelikovaAim: To evaluate the concurrent validity of the Hamilton Depression Rating Scale (HAMD-17) against ICD-10 criteria for depressive disorder and its performance as a screening and diagnostic tool for depression in patients with epilepsy (PWE).Subjects and Methods: One hundred and six PWE underwent clinical psychiatric examination followed by evaluation on HAMD-17. ICD-10 criteria for comorbid depressive disorder were applied. Internal consistency was assessed using Cronbach’s α. A “receiver operating characteristics” (ROC) curve was obtained and the sensitivity, specificity, positive and negative predictive values (PPV, NPV) were calculated for different cut-off points of the HAMD-17.Results: Internal consistency measured by Cronbach’s α was 0.74. Maximal discrimination between depressed and non depressed was obtained at a cut-off score of 8/9 (sensitivity 0.93, specificity 0.98). High sensitivity and NPV at the same cut-off score (sensitivity 0.93, NPV 1.0) show the screening properties, and high specificity and PPV at cut-offs 9/10, the diagnostic properties of the instrument. The area under the ROC curve (AUC=0.746) indicates the concurrent validity of the HAMD-17 score with the ICD-10 criteria for depressive disorder.Conclusion: The validity of the HAMD-17 against ICD-10 criteria for depressive disorder in PWE in our study is fair. The concurrent administration of diagnostic criteria can ascertain the presence of core symptoms of depression.http://www.journal-imab-bg.org/issue-2012/book3/JofIMAB2012vol18b3p305-307.pdfPsychometric propertiesHAMD-17Epilepsy |
| spellingShingle | Koraliya S. Todorova Valentina S. Velikova THE VALIDITY OF THE HAMILTON DEPRESSION RATING SCALE AS A SCREENING AND DIAGNOSTIC INSTRUMENT FOR DEPRESSION IN PATIENTS WITH EPILEPSY Journal of IMAB Psychometric properties HAMD-17 Epilepsy |
| title | THE VALIDITY OF THE HAMILTON DEPRESSION RATING SCALE AS A SCREENING AND DIAGNOSTIC INSTRUMENT FOR DEPRESSION IN PATIENTS WITH EPILEPSY |
| title_full | THE VALIDITY OF THE HAMILTON DEPRESSION RATING SCALE AS A SCREENING AND DIAGNOSTIC INSTRUMENT FOR DEPRESSION IN PATIENTS WITH EPILEPSY |
| title_fullStr | THE VALIDITY OF THE HAMILTON DEPRESSION RATING SCALE AS A SCREENING AND DIAGNOSTIC INSTRUMENT FOR DEPRESSION IN PATIENTS WITH EPILEPSY |
| title_full_unstemmed | THE VALIDITY OF THE HAMILTON DEPRESSION RATING SCALE AS A SCREENING AND DIAGNOSTIC INSTRUMENT FOR DEPRESSION IN PATIENTS WITH EPILEPSY |
| title_short | THE VALIDITY OF THE HAMILTON DEPRESSION RATING SCALE AS A SCREENING AND DIAGNOSTIC INSTRUMENT FOR DEPRESSION IN PATIENTS WITH EPILEPSY |
| title_sort | validity of the hamilton depression rating scale as a screening and diagnostic instrument for depression in patients with epilepsy |
| topic | Psychometric properties HAMD-17 Epilepsy |
| url | http://www.journal-imab-bg.org/issue-2012/book3/JofIMAB2012vol18b3p305-307.pdf |
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