NEW POSSIBILITIES FOR EVALUATION OF SEVERITY AND PROGNOSIS IN PATIENTS WITH CHRONIC HEART FAILURE BASED ON N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE PLASMA LEVEL
<p><strong>Aim.</strong> To study an importance of plasma N-terminal pro-brain natriuretic peptide (N-proBNP) in evaluation of severity and prognosis in patients with chronic heart failure (CHF) of ischemic genesis.</p><p><strong>Material and methods.</strong&g...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2016-01-01
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| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | http://www.rpcardio.ru/jour/article/view/707 |
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| author | A. S. Galjavich S. N. Merjasev R. A. Galjavi R. F. Merjaseva |
| author_facet | A. S. Galjavich S. N. Merjasev R. A. Galjavi R. F. Merjaseva |
| author_sort | A. S. Galjavich |
| collection | DOAJ |
| description | <p><strong>Aim.</strong> To study an importance of plasma N-terminal pro-brain natriuretic peptide (N-proBNP) in evaluation of severity and prognosis in patients with chronic heart failure (CHF) of ischemic genesis.</p><p><strong>Material and methods.</strong> 77 patients (60 men and 17 women; 59,4±10,7 y.o.) with CHF of ischemic genesis were included in the study. All patients had sinus rhythm and history of Q wave myocardial infarction. Standard examination was performed to all patients. Besides N-proBNP plasma level and patients yearly survival were evaluated.</p><p><strong>Results.</strong> N-proBNP plasma level had direct correlation with clinical indices (exercise tolerance, blood pressure, heart rate) and echocardiographic heart sizes. N-proBNP plasma level had relationship with prognosis of CHF patients. Baseline N-proBNP level was more than 2 times higher in died patients in comparison with survived patients. The yearly survival rate of CHF patients was 51,3% if N-proBNP level had been more than 400 fmol/ml (>15% of normal value). The clinico-laboratory index (based on N-proBNP plasma level) of severity and prognosis in CHF patients was developed.</p><p><strong>Conclusion.</strong> The clinico-laboratory index based on N-proBNP plasma level is easy to use and can improve medical practice.</p> |
| first_indexed | 2024-03-12T09:00:53Z |
| format | Article |
| id | doaj.art-1a1f4ab8cc3c4d58bf38fa4398fd3c72 |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-03-12T09:00:53Z |
| publishDate | 2016-01-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-1a1f4ab8cc3c4d58bf38fa4398fd3c722023-09-02T15:39:11ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-0155172110.1234/1819-6446-2009-5-17-21706NEW POSSIBILITIES FOR EVALUATION OF SEVERITY AND PROGNOSIS IN PATIENTS WITH CHRONIC HEART FAILURE BASED ON N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE PLASMA LEVELA. S. Galjavich0S. N. Merjasev1R. A. Galjavi2R. F. Merjaseva3Казанский государственный медицинский университетНижнекамская центральная районная больницаКазанский государственный медицинский университетНижнекамская центральная районная больница<p><strong>Aim.</strong> To study an importance of plasma N-terminal pro-brain natriuretic peptide (N-proBNP) in evaluation of severity and prognosis in patients with chronic heart failure (CHF) of ischemic genesis.</p><p><strong>Material and methods.</strong> 77 patients (60 men and 17 women; 59,4±10,7 y.o.) with CHF of ischemic genesis were included in the study. All patients had sinus rhythm and history of Q wave myocardial infarction. Standard examination was performed to all patients. Besides N-proBNP plasma level and patients yearly survival were evaluated.</p><p><strong>Results.</strong> N-proBNP plasma level had direct correlation with clinical indices (exercise tolerance, blood pressure, heart rate) and echocardiographic heart sizes. N-proBNP plasma level had relationship with prognosis of CHF patients. Baseline N-proBNP level was more than 2 times higher in died patients in comparison with survived patients. The yearly survival rate of CHF patients was 51,3% if N-proBNP level had been more than 400 fmol/ml (>15% of normal value). The clinico-laboratory index (based on N-proBNP plasma level) of severity and prognosis in CHF patients was developed.</p><p><strong>Conclusion.</strong> The clinico-laboratory index based on N-proBNP plasma level is easy to use and can improve medical practice.</p>http://www.rpcardio.ru/jour/article/view/707N-терминальный про-мозговой натрийуретический пептидхроническая сердечная недостаточностьвыживаемость |
| spellingShingle | A. S. Galjavich S. N. Merjasev R. A. Galjavi R. F. Merjaseva NEW POSSIBILITIES FOR EVALUATION OF SEVERITY AND PROGNOSIS IN PATIENTS WITH CHRONIC HEART FAILURE BASED ON N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE PLASMA LEVEL Рациональная фармакотерапия в кардиологии N-терминальный про-мозговой натрийуретический пептид хроническая сердечная недостаточность выживаемость |
| title | NEW POSSIBILITIES FOR EVALUATION OF SEVERITY AND PROGNOSIS IN PATIENTS WITH CHRONIC HEART FAILURE BASED ON N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE PLASMA LEVEL |
| title_full | NEW POSSIBILITIES FOR EVALUATION OF SEVERITY AND PROGNOSIS IN PATIENTS WITH CHRONIC HEART FAILURE BASED ON N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE PLASMA LEVEL |
| title_fullStr | NEW POSSIBILITIES FOR EVALUATION OF SEVERITY AND PROGNOSIS IN PATIENTS WITH CHRONIC HEART FAILURE BASED ON N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE PLASMA LEVEL |
| title_full_unstemmed | NEW POSSIBILITIES FOR EVALUATION OF SEVERITY AND PROGNOSIS IN PATIENTS WITH CHRONIC HEART FAILURE BASED ON N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE PLASMA LEVEL |
| title_short | NEW POSSIBILITIES FOR EVALUATION OF SEVERITY AND PROGNOSIS IN PATIENTS WITH CHRONIC HEART FAILURE BASED ON N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE PLASMA LEVEL |
| title_sort | new possibilities for evaluation of severity and prognosis in patients with chronic heart failure based on n terminal pro brain natriuretic peptide plasma level |
| topic | N-терминальный про-мозговой натрийуретический пептид хроническая сердечная недостаточность выживаемость |
| url | http://www.rpcardio.ru/jour/article/view/707 |
| work_keys_str_mv | AT asgaljavich newpossibilitiesforevaluationofseverityandprognosisinpatientswithchronicheartfailurebasedonnterminalprobrainnatriureticpeptideplasmalevel AT snmerjasev newpossibilitiesforevaluationofseverityandprognosisinpatientswithchronicheartfailurebasedonnterminalprobrainnatriureticpeptideplasmalevel AT ragaljavi newpossibilitiesforevaluationofseverityandprognosisinpatientswithchronicheartfailurebasedonnterminalprobrainnatriureticpeptideplasmalevel AT rfmerjaseva newpossibilitiesforevaluationofseverityandprognosisinpatientswithchronicheartfailurebasedonnterminalprobrainnatriureticpeptideplasmalevel |