Percutanous Electrochemotherapy (ECT) in Primary and Secondary Liver Malignancies: A Systematic Review
The aim of the study was to analyse papers describing the use of Electrochemotherapy (ECT) in local treatment of primary and secondary liver tumours located at different sites and with different histologies. Other Local Ablative Therapies (LAT) are also discussed. Analyses of these papers demonstrat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/2/209 |
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| author | Vincenza Granata Roberta Fusco Valeria D’Alessio Igino Simonetti Francesca Grassi Lucrezia Silvestro Raffaele Palaia Andrea Belli Renato Patrone Mauro Piccirillo Francesco Izzo |
| author_facet | Vincenza Granata Roberta Fusco Valeria D’Alessio Igino Simonetti Francesca Grassi Lucrezia Silvestro Raffaele Palaia Andrea Belli Renato Patrone Mauro Piccirillo Francesco Izzo |
| author_sort | Vincenza Granata |
| collection | DOAJ |
| description | The aim of the study was to analyse papers describing the use of Electrochemotherapy (ECT) in local treatment of primary and secondary liver tumours located at different sites and with different histologies. Other Local Ablative Therapies (LAT) are also discussed. Analyses of these papers demonstrate that ECT use is safe and effective in lesions of large size, independently of the histology of the treated lesions. ECT performed better than other thermal ablation techniques in lesions > 6 cm in size and can be safely used to treat lesions distant, close, or adjacent to vital structures. ECT spares vessel and bile ducts, is repeatable, and can be performed between chemotherapeutic cycles. ECT can fill the gap in local ablative therapies due to being lesions too large or localized in highly challenging anatomical sites. |
| first_indexed | 2024-03-09T13:03:28Z |
| format | Article |
| id | doaj.art-1a2047ed21864c8bbfc77472c69c710a |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T13:03:28Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-1a2047ed21864c8bbfc77472c69c710a2023-11-30T21:51:29ZengMDPI AGDiagnostics2075-44182023-01-0113220910.3390/diagnostics13020209Percutanous Electrochemotherapy (ECT) in Primary and Secondary Liver Malignancies: A Systematic ReviewVincenza Granata0Roberta Fusco1Valeria D’Alessio2Igino Simonetti3Francesca Grassi4Lucrezia Silvestro5Raffaele Palaia6Andrea Belli7Renato Patrone8Mauro Piccirillo9Francesco Izzo10Division of Radiology, Istituto Nazionale Tumori IRCCS Fondazione Pascale—IRCCS di Napoli, 80131 Naples, ItalyOncology Medical and Research & Development Division, Casalnuovo di Napoli, 80013 Naples, ItalyOncology Medical and Research & Development Division, Casalnuovo di Napoli, 80013 Naples, ItalyDivision of Radiology, Istituto Nazionale Tumori IRCCS Fondazione Pascale—IRCCS di Napoli, 80131 Naples, ItalyDivision of Radiology, Università degli Studi della Campania Luigi Vanvitelli, 80127 Naples, ItalyDivision of Clinical Experimental Oncology Abdomen, Istituto Nazionale Tumori IRCCS Fondazione Pascale—IRCCS di Napoli, 80131 Naples, ItalyDivision of Epatobiliary Surgical Oncology, Istituto Nazionale Tumori IRCCS Fondazione Pascale—IRCCS di Napoli, 80131 Naples, ItalyDivision of Epatobiliary Surgical Oncology, Istituto Nazionale Tumori IRCCS Fondazione Pascale—IRCCS di Napoli, 80131 Naples, ItalyDivision of Epatobiliary Surgical Oncology, Istituto Nazionale Tumori IRCCS Fondazione Pascale—IRCCS di Napoli, 80131 Naples, ItalyDivision of Epatobiliary Surgical Oncology, Istituto Nazionale Tumori IRCCS Fondazione Pascale—IRCCS di Napoli, 80131 Naples, ItalyDivision of Epatobiliary Surgical Oncology, Istituto Nazionale Tumori IRCCS Fondazione Pascale—IRCCS di Napoli, 80131 Naples, ItalyThe aim of the study was to analyse papers describing the use of Electrochemotherapy (ECT) in local treatment of primary and secondary liver tumours located at different sites and with different histologies. Other Local Ablative Therapies (LAT) are also discussed. Analyses of these papers demonstrate that ECT use is safe and effective in lesions of large size, independently of the histology of the treated lesions. ECT performed better than other thermal ablation techniques in lesions > 6 cm in size and can be safely used to treat lesions distant, close, or adjacent to vital structures. ECT spares vessel and bile ducts, is repeatable, and can be performed between chemotherapeutic cycles. ECT can fill the gap in local ablative therapies due to being lesions too large or localized in highly challenging anatomical sites.https://www.mdpi.com/2075-4418/13/2/209Electrochemotherapyliverpercutaneous approach |
| spellingShingle | Vincenza Granata Roberta Fusco Valeria D’Alessio Igino Simonetti Francesca Grassi Lucrezia Silvestro Raffaele Palaia Andrea Belli Renato Patrone Mauro Piccirillo Francesco Izzo Percutanous Electrochemotherapy (ECT) in Primary and Secondary Liver Malignancies: A Systematic Review Diagnostics Electrochemotherapy liver percutaneous approach |
| title | Percutanous Electrochemotherapy (ECT) in Primary and Secondary Liver Malignancies: A Systematic Review |
| title_full | Percutanous Electrochemotherapy (ECT) in Primary and Secondary Liver Malignancies: A Systematic Review |
| title_fullStr | Percutanous Electrochemotherapy (ECT) in Primary and Secondary Liver Malignancies: A Systematic Review |
| title_full_unstemmed | Percutanous Electrochemotherapy (ECT) in Primary and Secondary Liver Malignancies: A Systematic Review |
| title_short | Percutanous Electrochemotherapy (ECT) in Primary and Secondary Liver Malignancies: A Systematic Review |
| title_sort | percutanous electrochemotherapy ect in primary and secondary liver malignancies a systematic review |
| topic | Electrochemotherapy liver percutaneous approach |
| url | https://www.mdpi.com/2075-4418/13/2/209 |
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