BIOCOMPATIBILITY OF MEDICAL DEVICES BASED ON METALS, CAUSES FORMATION OF PATHOLOGICAL REACTIVITY (A REVIEW OF FOREIGN LITERATURE)
The objective of the research is a review of approaches to the evaluation of biocompatibility of medical devices on the basis of metals and alloys, and to find ways of overcoming the low engraftment of implanted structures. Implantation by artificial materials allows us to regain the use of human or...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2015-08-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/215 |
| _version_ | 1797872947676839936 |
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| author | O. M. Rozhnova V. V. Pavlov M. A. Sadovoy |
| author_facet | O. M. Rozhnova V. V. Pavlov M. A. Sadovoy |
| author_sort | O. M. Rozhnova |
| collection | DOAJ |
| description | The objective of the research is a review of approaches to the evaluation of biocompatibility of medical devices on the basis of metals and alloys, and to find ways of overcoming the low engraftment of implanted structures. Implantation by artificial materials allows us to regain the use of human organs and tissues and to date has no rivals. The advantage of using metals and alloys for implanted structures is their high reliability in operation, long servicelife, and high functionality. The nature of the interaction between the human body and the implant has an impact on resource use and the durability of the structures. Manufacturers of scientific research into medical implants at the present stage are directed to obtain materials that will not adversely affect the human body, and to ensure the maximum survival rate when using them. At the same time, the data presented in the article suggests that attempts to make higher biocompatible material properties tend to reduce the development of new methods for the surface treatment and the chemical composition modulation implants. World literature demonstrates the lack of a systematic approach to the problem of increased sensitivity of patients to different metals and alloys (metal sensitization), resulting in the development of complications such as the development of aseptic inflammation and infectious complications of unstable structures, and loss of functionality. Consequently, there is a need to search for ways to improve the biocompatibility of materials used in medicine, based on an assessment of immune defense mechanisms, and the development of algorithms preoperative tactics. |
| first_indexed | 2024-04-10T01:07:09Z |
| format | Article |
| id | doaj.art-1a299dcf55384dd0966c838c4995f0c9 |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:07:09Z |
| publishDate | 2015-08-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-1a299dcf55384dd0966c838c4995f0c92023-03-13T09:58:21ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842015-08-0114411011810.20538/1682-0363-2015-4-110-118213BIOCOMPATIBILITY OF MEDICAL DEVICES BASED ON METALS, CAUSES FORMATION OF PATHOLOGICAL REACTIVITY (A REVIEW OF FOREIGN LITERATURE)O. M. Rozhnova0V. V. Pavlov1M. A. Sadovoy2Новосибирский НИИ травматологии и ортопедии им. Я.Л. Цивьяна, НовосибирскНовосибирский НИИ травматологии и ортопедии им. Я.Л. Цивьяна, НовосибирскНовосибирский НИИ травматологии и ортопедии им. Я.Л. Цивьяна, НовосибирскThe objective of the research is a review of approaches to the evaluation of biocompatibility of medical devices on the basis of metals and alloys, and to find ways of overcoming the low engraftment of implanted structures. Implantation by artificial materials allows us to regain the use of human organs and tissues and to date has no rivals. The advantage of using metals and alloys for implanted structures is their high reliability in operation, long servicelife, and high functionality. The nature of the interaction between the human body and the implant has an impact on resource use and the durability of the structures. Manufacturers of scientific research into medical implants at the present stage are directed to obtain materials that will not adversely affect the human body, and to ensure the maximum survival rate when using them. At the same time, the data presented in the article suggests that attempts to make higher biocompatible material properties tend to reduce the development of new methods for the surface treatment and the chemical composition modulation implants. World literature demonstrates the lack of a systematic approach to the problem of increased sensitivity of patients to different metals and alloys (metal sensitization), resulting in the development of complications such as the development of aseptic inflammation and infectious complications of unstable structures, and loss of functionality. Consequently, there is a need to search for ways to improve the biocompatibility of materials used in medicine, based on an assessment of immune defense mechanisms, and the development of algorithms preoperative tactics.https://bulletin.ssmu.ru/jour/article/view/215биосовместимостьметаллическая аллергияимплантымедицинские материалы |
| spellingShingle | O. M. Rozhnova V. V. Pavlov M. A. Sadovoy BIOCOMPATIBILITY OF MEDICAL DEVICES BASED ON METALS, CAUSES FORMATION OF PATHOLOGICAL REACTIVITY (A REVIEW OF FOREIGN LITERATURE) Бюллетень сибирской медицины биосовместимость металлическая аллергия импланты медицинские материалы |
| title | BIOCOMPATIBILITY OF MEDICAL DEVICES BASED ON METALS, CAUSES FORMATION OF PATHOLOGICAL REACTIVITY (A REVIEW OF FOREIGN LITERATURE) |
| title_full | BIOCOMPATIBILITY OF MEDICAL DEVICES BASED ON METALS, CAUSES FORMATION OF PATHOLOGICAL REACTIVITY (A REVIEW OF FOREIGN LITERATURE) |
| title_fullStr | BIOCOMPATIBILITY OF MEDICAL DEVICES BASED ON METALS, CAUSES FORMATION OF PATHOLOGICAL REACTIVITY (A REVIEW OF FOREIGN LITERATURE) |
| title_full_unstemmed | BIOCOMPATIBILITY OF MEDICAL DEVICES BASED ON METALS, CAUSES FORMATION OF PATHOLOGICAL REACTIVITY (A REVIEW OF FOREIGN LITERATURE) |
| title_short | BIOCOMPATIBILITY OF MEDICAL DEVICES BASED ON METALS, CAUSES FORMATION OF PATHOLOGICAL REACTIVITY (A REVIEW OF FOREIGN LITERATURE) |
| title_sort | biocompatibility of medical devices based on metals causes formation of pathological reactivity a review of foreign literature |
| topic | биосовместимость металлическая аллергия импланты медицинские материалы |
| url | https://bulletin.ssmu.ru/jour/article/view/215 |
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