Effectiveness of the retreatment of patients with multibacillary leprosy and episodes of erythema nodosum leprosum and/or persistent neuritis: a single-center experience
Abstract: Background: Erythema nodosum leprosum may appear before, during or after treatment of leprosy and is one of the main factors for nerve damage in patients. When it occurs or continues to occur after treatment, it may indicate disease recurrence and a new treatment may be instituted again....
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2018-03-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/pdf/abd/v93n2/0365-0596-abd-93-02-0181.pdf |
| _version_ | 1818753826616770560 |
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| author | Joel Carlos Lastória Thaís Sampaio Corrêa de Almeida Maria Stella de Mello Ayres Putinatti Carlos Roberto Padovani |
| author_facet | Joel Carlos Lastória Thaís Sampaio Corrêa de Almeida Maria Stella de Mello Ayres Putinatti Carlos Roberto Padovani |
| author_sort | Joel Carlos Lastória |
| collection | DOAJ |
| description | Abstract: Background: Erythema nodosum leprosum may appear before, during or after treatment of leprosy and is one of the main factors for nerve damage in patients. When it occurs or continues to occur after treatment, it may indicate disease recurrence and a new treatment may be instituted again. Objective: To evaluate the retreatment of patients with multibacillary leprosy who underwent standard treatment with multidrug therapy, but developed or continued to present reactions of erythema nodosum leprosum and/or neuritis 3-5 years after its end. Method: For this objective, a new treatment was performed in 29 patients with multibacillary leprosy who maintained episodes of erythema nodosum and/or neuritis 3-5 years after conventional treatment. Results: In general, we observed that 27 (93.10%) had no more new episodes after a follow up period of eight months to five years. In five of these patients the reason for the retreatment was the occurrence of difficult-to-control neuritis, and that has ceased to occur in all of them. Study limitations: Small number of patients.. Conclusion: In the cases observed, retreatment was an effective measure to prevent the occurrence of erythema nodosum leprosum and/or persistent neuritis. |
| first_indexed | 2024-12-18T05:13:32Z |
| format | Article |
| id | doaj.art-1a2c572e390b4b20988996dfa50f89e6 |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-12-18T05:13:32Z |
| publishDate | 2018-03-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-1a2c572e390b4b20988996dfa50f89e62022-12-21T21:19:49ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962018-03-0193218118410.1590/abd1806-4841.20185387Effectiveness of the retreatment of patients with multibacillary leprosy and episodes of erythema nodosum leprosum and/or persistent neuritis: a single-center experienceJoel Carlos LastóriaThaís Sampaio Corrêa de AlmeidaMaria Stella de Mello Ayres PutinattiCarlos Roberto PadovaniAbstract: Background: Erythema nodosum leprosum may appear before, during or after treatment of leprosy and is one of the main factors for nerve damage in patients. When it occurs or continues to occur after treatment, it may indicate disease recurrence and a new treatment may be instituted again. Objective: To evaluate the retreatment of patients with multibacillary leprosy who underwent standard treatment with multidrug therapy, but developed or continued to present reactions of erythema nodosum leprosum and/or neuritis 3-5 years after its end. Method: For this objective, a new treatment was performed in 29 patients with multibacillary leprosy who maintained episodes of erythema nodosum and/or neuritis 3-5 years after conventional treatment. Results: In general, we observed that 27 (93.10%) had no more new episodes after a follow up period of eight months to five years. In five of these patients the reason for the retreatment was the occurrence of difficult-to-control neuritis, and that has ceased to occur in all of them. Study limitations: Small number of patients.. Conclusion: In the cases observed, retreatment was an effective measure to prevent the occurrence of erythema nodosum leprosum and/or persistent neuritis.http://www.scielo.br/pdf/abd/v93n2/0365-0596-abd-93-02-0181.pdfErythema nodosumLeprosyNeuritisRetreatment |
| spellingShingle | Joel Carlos Lastória Thaís Sampaio Corrêa de Almeida Maria Stella de Mello Ayres Putinatti Carlos Roberto Padovani Effectiveness of the retreatment of patients with multibacillary leprosy and episodes of erythema nodosum leprosum and/or persistent neuritis: a single-center experience Anais Brasileiros de Dermatologia Erythema nodosum Leprosy Neuritis Retreatment |
| title | Effectiveness of the retreatment of patients with multibacillary leprosy and episodes of erythema nodosum leprosum and/or persistent neuritis: a single-center experience |
| title_full | Effectiveness of the retreatment of patients with multibacillary leprosy and episodes of erythema nodosum leprosum and/or persistent neuritis: a single-center experience |
| title_fullStr | Effectiveness of the retreatment of patients with multibacillary leprosy and episodes of erythema nodosum leprosum and/or persistent neuritis: a single-center experience |
| title_full_unstemmed | Effectiveness of the retreatment of patients with multibacillary leprosy and episodes of erythema nodosum leprosum and/or persistent neuritis: a single-center experience |
| title_short | Effectiveness of the retreatment of patients with multibacillary leprosy and episodes of erythema nodosum leprosum and/or persistent neuritis: a single-center experience |
| title_sort | effectiveness of the retreatment of patients with multibacillary leprosy and episodes of erythema nodosum leprosum and or persistent neuritis a single center experience |
| topic | Erythema nodosum Leprosy Neuritis Retreatment |
| url | http://www.scielo.br/pdf/abd/v93n2/0365-0596-abd-93-02-0181.pdf |
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