Mesenchymal stromal cells attenuate sevoflurane-induced apoptosis in human neuroglioma H4 cells

Mesenchymal stromal cells attenuate sevoflurane-induced apoptosis in human neuroglioma H4 cells

Abstract Background Inhalation of sevoflurane can induce neuronal apoptosis, cognitive impairment and abnormal behaviors. Bone marrow mesenchymal stem cells (MSCs) can secret neurotrophic factors and cytokines to protect from oxidative stress-related neuronal apoptosis. However, whether MSCs can pro...

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Bibliographic Details
Main Authors: Yanyong Cheng, Yunfeng Jiang, Lei Zhang, Jiayi Wang, Dongdong Chai, Rong Hu, Chunzhu Li, Yu Sun, Hong Jiang
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Anesthesiology
Subjects:
Sevoflurane
Mesenchymal stem cells
Reactive oxygen species
Apoptosis, mitochondrial dysfunction
Online Access:http://link.springer.com/article/10.1186/s12871-018-0553-1

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