Health Disparities in Multiple Sclerosis among Hispanic and Black Populations in the United States

Multiple sclerosis (MS) is an acquired demyelinating disease of the central nervous system (CNS). Historically, research on MS has focused on White persons with MS. This preponderance of representation has important possible implications for minority populations with MS, from developing effective th...

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Main Authors: Michael Z. Moore, Carlos A. Pérez, George J. Hutton, Hemali Patel, Fernando X. Cuascut
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/4/1227
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author Michael Z. Moore
Carlos A. Pérez
George J. Hutton
Hemali Patel
Fernando X. Cuascut
author_facet Michael Z. Moore
Carlos A. Pérez
George J. Hutton
Hemali Patel
Fernando X. Cuascut
author_sort Michael Z. Moore
collection DOAJ
description Multiple sclerosis (MS) is an acquired demyelinating disease of the central nervous system (CNS). Historically, research on MS has focused on White persons with MS. This preponderance of representation has important possible implications for minority populations with MS, from developing effective therapeutic agents to understanding the role of unique constellations of social determinants of health. A growing body of literature involving persons of historically underrepresented races and ethnicities in the field of multiple sclerosis is assembling. Our purpose in this narrative review is to highlight two populations in the United States: Black and Hispanic persons with multiple sclerosis. We will review the current understanding about the patterns of disease presentation, genetic considerations, response to treatment, roles of social determinants of health, and healthcare utilization. In addition, we explore future directions of inquiry as well as practical methods of meeting these challenges.
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spelling doaj.art-1a31edabf74b4f9eb26b638eda9f60972023-11-17T18:28:18ZengMDPI AGBiomedicines2227-90592023-04-01114122710.3390/biomedicines11041227Health Disparities in Multiple Sclerosis among Hispanic and Black Populations in the United StatesMichael Z. Moore0Carlos A. Pérez1George J. Hutton2Hemali Patel3Fernando X. Cuascut4Maxine Mesinger Multiple Sclerosis Center, Baylor College of Medicine, Houston, TX 77030, USAMaxine Mesinger Multiple Sclerosis Center, Baylor College of Medicine, Houston, TX 77030, USAMaxine Mesinger Multiple Sclerosis Center, Baylor College of Medicine, Houston, TX 77030, USAMaxine Mesinger Multiple Sclerosis Center, Baylor College of Medicine, Houston, TX 77030, USAMaxine Mesinger Multiple Sclerosis Center, Baylor College of Medicine, Houston, TX 77030, USAMultiple sclerosis (MS) is an acquired demyelinating disease of the central nervous system (CNS). Historically, research on MS has focused on White persons with MS. This preponderance of representation has important possible implications for minority populations with MS, from developing effective therapeutic agents to understanding the role of unique constellations of social determinants of health. A growing body of literature involving persons of historically underrepresented races and ethnicities in the field of multiple sclerosis is assembling. Our purpose in this narrative review is to highlight two populations in the United States: Black and Hispanic persons with multiple sclerosis. We will review the current understanding about the patterns of disease presentation, genetic considerations, response to treatment, roles of social determinants of health, and healthcare utilization. In addition, we explore future directions of inquiry as well as practical methods of meeting these challenges.https://www.mdpi.com/2227-9059/11/4/1227MS—multiple sclerosisDMT—disease modifying therapiespwMS—persons with multiple sclerosisSDOH—social determinants of healthEDSS—Expanded Disability Severity ScaleSES—socioeconomic status
spellingShingle Michael Z. Moore
Carlos A. Pérez
George J. Hutton
Hemali Patel
Fernando X. Cuascut
Health Disparities in Multiple Sclerosis among Hispanic and Black Populations in the United States
Biomedicines
MS—multiple sclerosis
DMT—disease modifying therapies
pwMS—persons with multiple sclerosis
SDOH—social determinants of health
EDSS—Expanded Disability Severity Scale
SES—socioeconomic status
title Health Disparities in Multiple Sclerosis among Hispanic and Black Populations in the United States
title_full Health Disparities in Multiple Sclerosis among Hispanic and Black Populations in the United States
title_fullStr Health Disparities in Multiple Sclerosis among Hispanic and Black Populations in the United States
title_full_unstemmed Health Disparities in Multiple Sclerosis among Hispanic and Black Populations in the United States
title_short Health Disparities in Multiple Sclerosis among Hispanic and Black Populations in the United States
title_sort health disparities in multiple sclerosis among hispanic and black populations in the united states
topic MS—multiple sclerosis
DMT—disease modifying therapies
pwMS—persons with multiple sclerosis
SDOH—social determinants of health
EDSS—Expanded Disability Severity Scale
SES—socioeconomic status
url https://www.mdpi.com/2227-9059/11/4/1227
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