The Effect of Rivaroxaban on CYP4F2 and Transcription Factors’ Activity in HUVECs

The Effect of Rivaroxaban on CYP4F2 and Transcription Factors’ Activity in HUVECs

Interindividual variabilities between patients taking the anticoagulant rivaroxaban are a result of hepatic metabolism by CYP 450 enzymes. The objective of this study was to evaluate the impact of rivaroxaban on CYP4F2 and transcription factors’ activity in HUVECs. Rivaroxaban and its metabolites we...

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Bibliographic Details
Main Authors: Ieva Ciapiene, Vacis Tatarunas, Agne Giedraitiene, Vaidotas Zvikas, Valdas Jakstas, Audrone Veikutiene, Ugne Meskauskaite, Ugne Venckyte, Audrius Pukalskas, Vaiva Lesauskaite
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Applied Sciences
Subjects:
HUVECs
rivaroxaban
inflammation
hsa-miR-24-3p
CYP4F2
13-docosenamide
Online Access:https://www.mdpi.com/2076-3417/11/22/10851

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