iTRAQ-Based Quantitative Proteomic Analysis of Acinetobacter baumannii under Hypoxia and Normoxia Reveals the Role of OmpW as a Virulence Factor

iTRAQ-Based Quantitative Proteomic Analysis of Acinetobacter baumannii under Hypoxia and Normoxia Reveals the Role of OmpW as a Virulence Factor

ABSTRACT Acinetobacter baumannii needs to adapt to hypoxia during infection. Understanding its proteome regulation during infection would allow us to determine new targets to develop novel treatments. iTRAQ proteomic analysis of A549 cell infection by the ATCC 17978 strain was performed. A total of...

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Bibliographic Details
Main Authors: María Luisa Gil-Marqués, Jerónimo Pachón, Younes Smani
Format: Article
Language:English
Published: American Society for Microbiology 2022-04-01
Series:Microbiology Spectrum
Subjects:
hypoxia
Acinetobacter baumannii
iTRAQ
virulence factors
OmpW
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02328-21

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