Effects of Vitamin D Levels on Quality of Life in Osteoporosis - Original Investigation
Vitamin D deficiency causes muscle weakness, impairs bone formation and neuromuscular coordination, thus increases fracture risk. It is well known that pain and functional disability caused by fractures impairs quality of life (QOL). However, studies investigating the association between vitamin D d...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2006-06-01
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| Series: | Türk Osteoporoz Dergisi |
| Subjects: | |
| Online Access: | http://www.turkosteoporozdergisi.org/article_4159/Effects-Of-Vitamin-D-Levels-On-Quality-Of-Life-In-Osteoporosis-Original-Investigation |
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| author | İlker Coşkun Benlidayı Füsun Güler Uysal Sibel Başaran Rengin Güzel |
| author_facet | İlker Coşkun Benlidayı Füsun Güler Uysal Sibel Başaran Rengin Güzel |
| author_sort | İlker Coşkun Benlidayı |
| collection | DOAJ |
| description | Vitamin D deficiency causes muscle weakness, impairs bone formation and neuromuscular coordination, thus increases fracture risk. It is well known that pain and functional disability caused by fractures impairs quality of life (QOL). However, studies investigating the association between vitamin D deficiency and QOL are insufficient. This study investigates the effects of vitamin D level on QOL in osteoporotic patients.
286 patients (mean age 60.51±9.1 years) with postmenapousal, senile or male osteoporosis were included in the study. Demographic data, physical activity level and back pain were recorded. Bone turnover markers, 25(OH)vitaminD, PTH levels and bone mineral density (BMD) were evaluated. Spinal deformity index (SDI) was calculated by lateral thoracolomber X-rays. QOL was assessed using QOL Questionnaire of the European Foundation for Osteoporosis (QUALEFFO). 25(OH)vitaminD levels below 12ng/ml was accepted as vitamin D deficiency.
25(OH)vitaminD level of the patients was 23.19±13.1ng/ml and 34 were (11.8%) vitamin D deficient. 25(OH)vitaminD levels were not correlated with age, body mass index, concomitant diseases, postmenopausal years, risk factors, pain, and dietary calcium intake. There was also no correlation between 25(OH)vitaminD and bone turnover markers, SDI and BMD. 25(OH)vitaminD was correlated with physical activity level (p=0.001 and r=0.198) and physical, social, mental function subscales and total score of QUALEFFO. In vitamin D deficient group physical and social function subscales and total QUALEFFO scores were more impaired (p=0.001, p=0.004, p=0.003 respectively).
Vitamin D deficiency negatively effects physical and social functions of osteoporotic patients and impairs their QOL. (Osteoporoz Dünyasından 2006; 12 (2): 35-38) |
| first_indexed | 2024-04-10T12:13:11Z |
| format | Article |
| id | doaj.art-1a424e17bcea4858a1e67dab2277e6ca |
| institution | Directory Open Access Journal |
| issn | 2147-2653 |
| language | English |
| last_indexed | 2024-04-10T12:13:11Z |
| publishDate | 2006-06-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Osteoporoz Dergisi |
| spelling | doaj.art-1a424e17bcea4858a1e67dab2277e6ca2023-02-15T16:15:55ZengGalenos YayineviTürk Osteoporoz Dergisi2147-26532006-06-011223538Effects of Vitamin D Levels on Quality of Life in Osteoporosis - Original Investigationİlker Coşkun Benlidayı0Füsun Güler Uysal1Sibel Başaran2Rengin Güzel3Çukurova Üniversitesi Tıp Fakültesi Fiziksel Tıp ve Rehabilitasyon Anabilim DalıÇukurova Üniversitesi Tıp Fakültesi Fiziksel Tıp ve Rehabilitasyon Anabilim DalıÇukurova Üniversitesi Tıp Fakültesi Fiziksel Tıp ve Rehabilitasyon Anabilim DalıÇukurova Üniversitesi Tıp Fakültesi Fiziksel Tıp ve Rehabilitasyon Anabilim DalıVitamin D deficiency causes muscle weakness, impairs bone formation and neuromuscular coordination, thus increases fracture risk. It is well known that pain and functional disability caused by fractures impairs quality of life (QOL). However, studies investigating the association between vitamin D deficiency and QOL are insufficient. This study investigates the effects of vitamin D level on QOL in osteoporotic patients. 286 patients (mean age 60.51±9.1 years) with postmenapousal, senile or male osteoporosis were included in the study. Demographic data, physical activity level and back pain were recorded. Bone turnover markers, 25(OH)vitaminD, PTH levels and bone mineral density (BMD) were evaluated. Spinal deformity index (SDI) was calculated by lateral thoracolomber X-rays. QOL was assessed using QOL Questionnaire of the European Foundation for Osteoporosis (QUALEFFO). 25(OH)vitaminD levels below 12ng/ml was accepted as vitamin D deficiency. 25(OH)vitaminD level of the patients was 23.19±13.1ng/ml and 34 were (11.8%) vitamin D deficient. 25(OH)vitaminD levels were not correlated with age, body mass index, concomitant diseases, postmenopausal years, risk factors, pain, and dietary calcium intake. There was also no correlation between 25(OH)vitaminD and bone turnover markers, SDI and BMD. 25(OH)vitaminD was correlated with physical activity level (p=0.001 and r=0.198) and physical, social, mental function subscales and total score of QUALEFFO. In vitamin D deficient group physical and social function subscales and total QUALEFFO scores were more impaired (p=0.001, p=0.004, p=0.003 respectively). Vitamin D deficiency negatively effects physical and social functions of osteoporotic patients and impairs their QOL. (Osteoporoz Dünyasından 2006; 12 (2): 35-38)http://www.turkosteoporozdergisi.org/article_4159/Effects-Of-Vitamin-D-Levels-On-Quality-Of-Life-In-Osteoporosis-Original-InvestigationVitamin Dosteoporosisquality of lifeQUALEFFO |
| spellingShingle | İlker Coşkun Benlidayı Füsun Güler Uysal Sibel Başaran Rengin Güzel Effects of Vitamin D Levels on Quality of Life in Osteoporosis - Original Investigation Türk Osteoporoz Dergisi Vitamin D osteoporosis quality of life QUALEFFO |
| title | Effects of Vitamin D Levels on Quality of Life in Osteoporosis - Original Investigation |
| title_full | Effects of Vitamin D Levels on Quality of Life in Osteoporosis - Original Investigation |
| title_fullStr | Effects of Vitamin D Levels on Quality of Life in Osteoporosis - Original Investigation |
| title_full_unstemmed | Effects of Vitamin D Levels on Quality of Life in Osteoporosis - Original Investigation |
| title_short | Effects of Vitamin D Levels on Quality of Life in Osteoporosis - Original Investigation |
| title_sort | effects of vitamin d levels on quality of life in osteoporosis original investigation |
| topic | Vitamin D osteoporosis quality of life QUALEFFO |
| url | http://www.turkosteoporozdergisi.org/article_4159/Effects-Of-Vitamin-D-Levels-On-Quality-Of-Life-In-Osteoporosis-Original-Investigation |
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