Label-free imaging and classification of live P. falciparum enables high performance parasitemia quantification without fixation or staining.
Manual microscopic inspection of fixed and stained blood smears has remained the gold standard for Plasmodium parasitemia analysis for over a century. Unfortunately, smear preparation consumes time and reagents, while manual microscopy is skill-dependent and labor-intensive. Here, we demonstrate tha...
Main Authors: | Paul Lebel, Rebekah Dial, Venkata N P Vemuri, Valentina Garcia, Joseph DeRisi, Rafael Gómez-Sjöberg |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-08-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1009257 |
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