In vivo dynamics of acidosis and oxidative stress in the acute phase of an ischemic stroke in a rodent model

In vivo dynamics of acidosis and oxidative stress in the acute phase of an ischemic stroke in a rodent model

Ischemic cerebral stroke is one of the leading causes of death and disability in humans. However, molecular processes underlying the development of this pathology remain poorly understood. There are major gaps in our understanding of metabolic changes that occur in the brain tissue during the early...

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Main Authors: Ilya V. Kelmanson, Arina G. Shokhina, Daria A. Kotova, Matvei S. Pochechuev, Alexandra D. Ivanova, Alexander I. Kostyuk, Anastasiya S. Panova, Anastasia A. Borodinova, Maxim A. Solotenkov, Evgeny A. Stepanov, Roman I. Raevskii, Aleksandr A. Moshchenko, Valeriy V. Pak, Yulia G. Ermakova, Gijsbert J.C. van Belle, Viktor Tarabykin, Pavel M. Balaban, Ilya V. Fedotov, Andrei B. Fedotov, Marcus Conrad, Ivan Bogeski, Dörthe M. Katschinski, Thorsten R. Doeppner, Mathias Bähr, Aleksei M. Zheltikov, Vsevolod V. Belousov, Dmitry S. Bilan
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Redox Biology
Subjects:
Ischemic stroke
Ischemia/reperfusion
Hypoxia/reoxygenation
In vivo optical brain interrogation
Genetically encoded fluorescent biosensors
Hydrogen peroxide
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721003384

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