Nanodelivery of Dietary Polyphenols for Therapeutic Applications

Advancement in nanotechnology has unleashed the therapeutic potentials of dietary polyphenols by enhancing bioavailability, improving biological half-life, and allowing site-specific drug delivery. In this review, through citation of relevant literature reports, we discuss the application of nano-ph...

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Main Authors: Mithun Rudrapal, Ashwini K. Mishra, Laxmi Rani, Khomendra K. Sarwa, James H. Zothantluanga, Johra Khan, Mehnaz Kamal, Santwana Palai, Atul R. Bendale, Swati G. Talele, Vasim T. Pathan, Laxmikant B. Borse, Vishnu S. Neharkar, Pravat K. Sahoo
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/24/8706
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author Mithun Rudrapal
Ashwini K. Mishra
Laxmi Rani
Khomendra K. Sarwa
James H. Zothantluanga
Johra Khan
Mehnaz Kamal
Santwana Palai
Atul R. Bendale
Swati G. Talele
Vasim T. Pathan
Laxmikant B. Borse
Vishnu S. Neharkar
Pravat K. Sahoo
author_facet Mithun Rudrapal
Ashwini K. Mishra
Laxmi Rani
Khomendra K. Sarwa
James H. Zothantluanga
Johra Khan
Mehnaz Kamal
Santwana Palai
Atul R. Bendale
Swati G. Talele
Vasim T. Pathan
Laxmikant B. Borse
Vishnu S. Neharkar
Pravat K. Sahoo
author_sort Mithun Rudrapal
collection DOAJ
description Advancement in nanotechnology has unleashed the therapeutic potentials of dietary polyphenols by enhancing bioavailability, improving biological half-life, and allowing site-specific drug delivery. In this review, through citation of relevant literature reports, we discuss the application of nano-pharmaceutical formulations, such as solid lipid nanoparticles, nano-emulsions, nano-crystals, nano-polymersomes, liposomes, ethosomes, phytosomes, and invasomes for dietary polyphenols. Following this, we highlight important studies concerning different combinations of nano formulations with dietary polyphenols (also known as nanophytopolyphenols). We also provide nano-formulation paradigms for enhancing the physicochemical properties of dietary polyphenols. Finally, we highlight the latest patents that were granted on nano-formulations of dietary polyphenols. Based on our review, we observe that nanosized delivery of herbal constituents, spices, and dietary supplements have the ability to improve biological processes and address issues connected with herbal treatments.
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spelling doaj.art-1a4692fe62db4406b0586d8ecb0c0b3d2023-11-24T16:56:04ZengMDPI AGMolecules1420-30492022-12-012724870610.3390/molecules27248706Nanodelivery of Dietary Polyphenols for Therapeutic ApplicationsMithun Rudrapal0Ashwini K. Mishra1Laxmi Rani2Khomendra K. Sarwa3James H. Zothantluanga4Johra Khan5Mehnaz Kamal6Santwana Palai7Atul R. Bendale8Swati G. Talele9Vasim T. Pathan10Laxmikant B. Borse11Vishnu S. Neharkar12Pravat K. Sahoo13Department of Pharmaceutical Chemistry, Rasiklal M. Dhariwal Institute of Pharmaceutical Education and Research, Pune 411019, IndiaDepartment of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, IndiaDepartment of Pharmacy, School of Medical and Allied Sciences, GD Goenka University, Gurugram 122103, IndiaDepartment of Pharmacy, Government Girls Polytechnic, Raipur 492001, IndiaDepartment of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh 786004, IndiaDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al-Majmaah 11952, Saudi ArabiaDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi ArabiaDepartment of Veterinary Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, Orissa University of Agriculture and Technology (OUAT), Bhubaneswar 751003, IndiaSandip Institute of Pharmaceutical Sciences, Nashik 422213, IndiaSandip Institute of Pharmaceutical Sciences, Nashik 422213, IndiaSandip Institute of Pharmaceutical Sciences, Nashik 422213, IndiaSandip Institute of Pharmaceutical Sciences, Nashik 422213, IndiaDepartment of Pharmacology, Rasiklal M. Dhariwal Institute of Pharmaceutical Education and Research, Pune 411019, IndiaDepartment of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, IndiaAdvancement in nanotechnology has unleashed the therapeutic potentials of dietary polyphenols by enhancing bioavailability, improving biological half-life, and allowing site-specific drug delivery. In this review, through citation of relevant literature reports, we discuss the application of nano-pharmaceutical formulations, such as solid lipid nanoparticles, nano-emulsions, nano-crystals, nano-polymersomes, liposomes, ethosomes, phytosomes, and invasomes for dietary polyphenols. Following this, we highlight important studies concerning different combinations of nano formulations with dietary polyphenols (also known as nanophytopolyphenols). We also provide nano-formulation paradigms for enhancing the physicochemical properties of dietary polyphenols. Finally, we highlight the latest patents that were granted on nano-formulations of dietary polyphenols. Based on our review, we observe that nanosized delivery of herbal constituents, spices, and dietary supplements have the ability to improve biological processes and address issues connected with herbal treatments.https://www.mdpi.com/1420-3049/27/24/8706dietary polyphenolsnanotechnologynanoformulationnanophytomedicinenanodelivery
spellingShingle Mithun Rudrapal
Ashwini K. Mishra
Laxmi Rani
Khomendra K. Sarwa
James H. Zothantluanga
Johra Khan
Mehnaz Kamal
Santwana Palai
Atul R. Bendale
Swati G. Talele
Vasim T. Pathan
Laxmikant B. Borse
Vishnu S. Neharkar
Pravat K. Sahoo
Nanodelivery of Dietary Polyphenols for Therapeutic Applications
Molecules
dietary polyphenols
nanotechnology
nanoformulation
nanophytomedicine
nanodelivery
title Nanodelivery of Dietary Polyphenols for Therapeutic Applications
title_full Nanodelivery of Dietary Polyphenols for Therapeutic Applications
title_fullStr Nanodelivery of Dietary Polyphenols for Therapeutic Applications
title_full_unstemmed Nanodelivery of Dietary Polyphenols for Therapeutic Applications
title_short Nanodelivery of Dietary Polyphenols for Therapeutic Applications
title_sort nanodelivery of dietary polyphenols for therapeutic applications
topic dietary polyphenols
nanotechnology
nanoformulation
nanophytomedicine
nanodelivery
url https://www.mdpi.com/1420-3049/27/24/8706
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