Reversible dementia due to Neurocysticercosis: improvement of the racemose type with antihistamines
Infection of the human central nervous system (CNS) by the larvae of Taenia solium, termed neurocysticercosis (NCC), is endemic in most developing countries, where it is a major cause of acquired seizures and other neurological morbidity, including neuropsychiatric symptoms. However, despite its fre...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Associação Neurologia Cognitiva e do Comportamento
|
| Series: | Dementia & Neuropsychologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642015000100085&lng=en&tlng=en |
| _version_ | 1818020425203974144 |
|---|---|
| author | Gislaine Cristina Lopes Machado-Porto Leandro Tavares Lucato Fábio Henrique de Gobbi Porto Evandro Cesar de Souza Ricardo Nitrini |
| author_facet | Gislaine Cristina Lopes Machado-Porto Leandro Tavares Lucato Fábio Henrique de Gobbi Porto Evandro Cesar de Souza Ricardo Nitrini |
| author_sort | Gislaine Cristina Lopes Machado-Porto |
| collection | DOAJ |
| description | Infection of the human central nervous system (CNS) by the larvae of Taenia solium, termed neurocysticercosis (NCC), is endemic in most developing countries, where it is a major cause of acquired seizures and other neurological morbidity, including neuropsychiatric symptoms. However, despite its frequent manifestation, some findings, such as cognitive impairment and dementia, remain poorly understood. Less commonly, NCC may affect the ventricular system and subarachnoid spaces and this form is known as extraparenchymal neurocysticercosis. A particular presentation of the subarachnoid form is called racemose cysticercosis, which has a progressive pattern, frequently leads to hydrocephalus and can be life-threatening. Here we review a case of the racemose variety of cysticercosis, complicated by hydrocephalus and reversible dementia, with remission of symptoms after derivation and that remained stable with use of dexchlorpheniramine. We discuss the challenges in diagnosis, imaging findings, treatment and follow-up of this disease. |
| first_indexed | 2024-04-14T08:04:57Z |
| format | Article |
| id | doaj.art-1a4958262b6046b38cad623fe313ec11 |
| institution | Directory Open Access Journal |
| issn | 1980-5764 |
| language | English |
| last_indexed | 2024-04-14T08:04:57Z |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| record_format | Article |
| series | Dementia & Neuropsychologia |
| spelling | doaj.art-1a4958262b6046b38cad623fe313ec112022-12-22T02:04:46ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-576491859010.1590/S1980-57642015DN91000014S1980-57642015000100085Reversible dementia due to Neurocysticercosis: improvement of the racemose type with antihistaminesGislaine Cristina Lopes Machado-PortoLeandro Tavares LucatoFábio Henrique de Gobbi PortoEvandro Cesar de SouzaRicardo NitriniInfection of the human central nervous system (CNS) by the larvae of Taenia solium, termed neurocysticercosis (NCC), is endemic in most developing countries, where it is a major cause of acquired seizures and other neurological morbidity, including neuropsychiatric symptoms. However, despite its frequent manifestation, some findings, such as cognitive impairment and dementia, remain poorly understood. Less commonly, NCC may affect the ventricular system and subarachnoid spaces and this form is known as extraparenchymal neurocysticercosis. A particular presentation of the subarachnoid form is called racemose cysticercosis, which has a progressive pattern, frequently leads to hydrocephalus and can be life-threatening. Here we review a case of the racemose variety of cysticercosis, complicated by hydrocephalus and reversible dementia, with remission of symptoms after derivation and that remained stable with use of dexchlorpheniramine. We discuss the challenges in diagnosis, imaging findings, treatment and follow-up of this disease.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642015000100085&lng=en&tlng=enneurocysticercosisracemose formTaenia soliumdexchlorpheniraminedementiareversible dementiaantihistamine |
| spellingShingle | Gislaine Cristina Lopes Machado-Porto Leandro Tavares Lucato Fábio Henrique de Gobbi Porto Evandro Cesar de Souza Ricardo Nitrini Reversible dementia due to Neurocysticercosis: improvement of the racemose type with antihistamines Dementia & Neuropsychologia neurocysticercosis racemose form Taenia solium dexchlorpheniramine dementia reversible dementia antihistamine |
| title | Reversible dementia due to Neurocysticercosis: improvement of the racemose type with antihistamines |
| title_full | Reversible dementia due to Neurocysticercosis: improvement of the racemose type with antihistamines |
| title_fullStr | Reversible dementia due to Neurocysticercosis: improvement of the racemose type with antihistamines |
| title_full_unstemmed | Reversible dementia due to Neurocysticercosis: improvement of the racemose type with antihistamines |
| title_short | Reversible dementia due to Neurocysticercosis: improvement of the racemose type with antihistamines |
| title_sort | reversible dementia due to neurocysticercosis improvement of the racemose type with antihistamines |
| topic | neurocysticercosis racemose form Taenia solium dexchlorpheniramine dementia reversible dementia antihistamine |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642015000100085&lng=en&tlng=en |
| work_keys_str_mv | AT gislainecristinalopesmachadoporto reversibledementiaduetoneurocysticercosisimprovementoftheracemosetypewithantihistamines AT leandrotavareslucato reversibledementiaduetoneurocysticercosisimprovementoftheracemosetypewithantihistamines AT fabiohenriquedegobbiporto reversibledementiaduetoneurocysticercosisimprovementoftheracemosetypewithantihistamines AT evandrocesardesouza reversibledementiaduetoneurocysticercosisimprovementoftheracemosetypewithantihistamines AT ricardonitrini reversibledementiaduetoneurocysticercosisimprovementoftheracemosetypewithantihistamines |