Worsening glycemic control in youth with type 2 diabetes during COVID-19
IntroductionThe COVID-19 pandemic has disproportionately affected minority and lower socioeconomic populations, who also have higher rates of type 2 diabetes (T2D). The impact of virtual school, decreased activity level, and worsening food insecurity on pediatric T2D is unknown. The goal of this stu...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Clinical Diabetes and Healthcare |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcdhc.2022.968113/full |
| _version_ | 1811274257239375872 |
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| author | Sonum Bharill Tyger Lin Alexander Arking Elizabeth A. Brown Margaret West Kelly Busin Sheela N. Magge Risa M. Wolf |
| author_facet | Sonum Bharill Tyger Lin Alexander Arking Elizabeth A. Brown Margaret West Kelly Busin Sheela N. Magge Risa M. Wolf |
| author_sort | Sonum Bharill |
| collection | DOAJ |
| description | IntroductionThe COVID-19 pandemic has disproportionately affected minority and lower socioeconomic populations, who also have higher rates of type 2 diabetes (T2D). The impact of virtual school, decreased activity level, and worsening food insecurity on pediatric T2D is unknown. The goal of this study was to evaluate weight trends and glycemic control in youth with existing T2D during the COVID-19 pandemic.MethodsA retrospective study of youth <21 years of age diagnosed with T2D prior to March 11, 2020 was conducted at an academic pediatric diabetes center to compare glycemic control, weight, and BMI in the year prior to the COVID-19 pandemic (March 2019-2020) to during COVID-19 (March 2020-2021). Paired t-tests and linear mixed effects models were used to analyze changes during this period.ResultsA total of 63 youth with T2D were included (median age 15.0 (IQR 14-16) years, 59% female, 74.6% black, 14.3% Hispanic, 77.8% with Medicaid insurance). Median duration of diabetes was 0.8 (IQR 0.2-2.0) years. There was no difference in weight or BMI from the pre-COVID-19 period compared to during COVID-19 (Weight: 101.5 v 102.9 kg, p=0.18; BMI: 36.0 v 36.1 kg/m2, p=0.72). Hemoglobin A1c significantly increased during COVID-19 (7.6% vs 8.6%, p=0.0002)ConclusionWhile hemoglobin A1c increased significantly in youth with T2D during the COVID-19 pandemic, there was no significant change in weight or BMI possibly due to glucosuria associated with hyperglycemia. Youth with T2D are at high risk for diabetes complications, and the worsening glycemic control in this population highlights the need to prioritize close follow-up and disease management to prevent further metabolic decompensation. |
| first_indexed | 2024-04-12T23:15:44Z |
| format | Article |
| id | doaj.art-1a49e668bd274ee0b1a52d6042e51a9d |
| institution | Directory Open Access Journal |
| issn | 2673-6616 |
| language | English |
| last_indexed | 2024-04-12T23:15:44Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Clinical Diabetes and Healthcare |
| spelling | doaj.art-1a49e668bd274ee0b1a52d6042e51a9d2022-12-22T03:12:40ZengFrontiers Media S.A.Frontiers in Clinical Diabetes and Healthcare2673-66162022-09-01310.3389/fcdhc.2022.968113968113Worsening glycemic control in youth with type 2 diabetes during COVID-19Sonum BharillTyger LinAlexander ArkingElizabeth A. BrownMargaret WestKelly BusinSheela N. MaggeRisa M. WolfIntroductionThe COVID-19 pandemic has disproportionately affected minority and lower socioeconomic populations, who also have higher rates of type 2 diabetes (T2D). The impact of virtual school, decreased activity level, and worsening food insecurity on pediatric T2D is unknown. The goal of this study was to evaluate weight trends and glycemic control in youth with existing T2D during the COVID-19 pandemic.MethodsA retrospective study of youth <21 years of age diagnosed with T2D prior to March 11, 2020 was conducted at an academic pediatric diabetes center to compare glycemic control, weight, and BMI in the year prior to the COVID-19 pandemic (March 2019-2020) to during COVID-19 (March 2020-2021). Paired t-tests and linear mixed effects models were used to analyze changes during this period.ResultsA total of 63 youth with T2D were included (median age 15.0 (IQR 14-16) years, 59% female, 74.6% black, 14.3% Hispanic, 77.8% with Medicaid insurance). Median duration of diabetes was 0.8 (IQR 0.2-2.0) years. There was no difference in weight or BMI from the pre-COVID-19 period compared to during COVID-19 (Weight: 101.5 v 102.9 kg, p=0.18; BMI: 36.0 v 36.1 kg/m2, p=0.72). Hemoglobin A1c significantly increased during COVID-19 (7.6% vs 8.6%, p=0.0002)ConclusionWhile hemoglobin A1c increased significantly in youth with T2D during the COVID-19 pandemic, there was no significant change in weight or BMI possibly due to glucosuria associated with hyperglycemia. Youth with T2D are at high risk for diabetes complications, and the worsening glycemic control in this population highlights the need to prioritize close follow-up and disease management to prevent further metabolic decompensation.https://www.frontiersin.org/articles/10.3389/fcdhc.2022.968113/fulltype 2 diabetes (T2D)Coronavirus – COVID-19A1C (or HbA1c)hemoglobin A1cglycemic controladolescent |
| spellingShingle | Sonum Bharill Tyger Lin Alexander Arking Elizabeth A. Brown Margaret West Kelly Busin Sheela N. Magge Risa M. Wolf Worsening glycemic control in youth with type 2 diabetes during COVID-19 Frontiers in Clinical Diabetes and Healthcare type 2 diabetes (T2D) Coronavirus – COVID-19 A1C (or HbA1c) hemoglobin A1c glycemic control adolescent |
| title | Worsening glycemic control in youth with type 2 diabetes during COVID-19 |
| title_full | Worsening glycemic control in youth with type 2 diabetes during COVID-19 |
| title_fullStr | Worsening glycemic control in youth with type 2 diabetes during COVID-19 |
| title_full_unstemmed | Worsening glycemic control in youth with type 2 diabetes during COVID-19 |
| title_short | Worsening glycemic control in youth with type 2 diabetes during COVID-19 |
| title_sort | worsening glycemic control in youth with type 2 diabetes during covid 19 |
| topic | type 2 diabetes (T2D) Coronavirus – COVID-19 A1C (or HbA1c) hemoglobin A1c glycemic control adolescent |
| url | https://www.frontiersin.org/articles/10.3389/fcdhc.2022.968113/full |
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