Astragaloside IV attenuates sunitinib-associated cardiotoxicity by inhibiting COUP-TFII

Astragaloside IV attenuates sunitinib-associated cardiotoxicity by inhibiting COUP-TFII

Sunitinib (SU) is widely used to treat solid tumors but it can be cardiotoxic and often leads to drug withdrawn or discontinuation. Astragaloside IV (ASIV) is the essential active component of the Chinese herb Astragalus membranaceus which shows potential cardioprotective effects. Herein, we investi...

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Bibliografiska uppgifter
Huvudupphovsmän: Wanting Qin, Shaoling Li, Ziji Cheng, Wenlong Xue, Mingyue Tian, Fangfang Mou, Haidong Guo, Shuijin Shao, Baonian Liu
Materialtyp: Artikel
Språk:English
Publicerad: Elsevier 2024-02-01
Serie:Heliyon
Ämnen:
Astragaloside IV
Sunitinib-associated cardiotoxicity
COUP-TFII
Oxidative stress
Apoptosis
Länkar:http://www.sciencedirect.com/science/article/pii/S2405844024008107

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http://www.sciencedirect.com/science/article/pii/S2405844024008107

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