ANALYSIS OF POSSIBLE POSITIVE EFFECTS OF OXYTOCIN ADMINISTERED DURING BIRTH ON THE NEUROMOTOR DEVELOPMENT OF THE 0 - 5 YEAR-OLD-CHILDREN
Neuropeptide oxytocin (OT) receives increasing attention since, it plays a role in various behaviors including anxiety, drug addiction, learning, social recognition, empathy, pair bonding and decreased aggression. The central nucleus of the amygdala (CeA), part of the limbic system, plays an importa...
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| Format: | Article |
| Language: | English |
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Romanian Foundation for Business Intelligence
2017-05-01
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| Series: | SEA: Practical Application of Science |
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| Online Access: |
http://seaopenresearch.eu/Journals/articles/SPAS_13_18.pdf
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| _version_ | 1818155373854457856 |
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| author | Iulia Elena DIACONU Carmen Rodica ANTON Emil ANTON Dumitru FILIPEANU |
| author_facet | Iulia Elena DIACONU Carmen Rodica ANTON Emil ANTON Dumitru FILIPEANU |
| author_sort | Iulia Elena DIACONU |
| collection | DOAJ |
| description | Neuropeptide oxytocin (OT) receives increasing attention since, it plays a role in various behaviors including anxiety, drug addiction, learning, social recognition, empathy, pair bonding and decreased aggression. The central nucleus of the amygdala (CeA), part of the limbic system, plays an important role in learning, memory, anxiety and reinforcing mechanisms. Oxytocin receptors are found in the tissues of the cardiovascular system, reproductive system, brain, and are activated by exposure to specific stimuli. The bestknown stimuli related to reproduction are sucking, birth, cervical stimulation during sexual intercourse. Changes in the oxytocinergic system play a fundamental role in the development of autism, mental disorders, including eating disorders, obsessive-compulsive disorder, schizophrenia, with direct impact on the patient’s cognition and social behavior. Some researchers have observed that intranasal Oxytocin (OT) is a potential treatment for multiple neuropsychiatric disorders. As oxytocin is a peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies. Although studies have shown increased cerebrospinal fluid oxytocin levels following intranasal administration, this does not unequivocably demonstrate that the peripherally administered oxytocin is entering the cerebrospinal fluid. For example, it has been suggested that peripheral delivery of oxytocin could lead to central release of endogenous oxytocin. It is also unknown whether the intranasal route provides for more efficient entry of the peptide into the CSF compared to the intravenous (IV) route, which requires blood–brain barrier penetration. |
| first_indexed | 2024-12-11T14:41:23Z |
| format | Article |
| id | doaj.art-1a5638959e584a66bab0a50b075d258d |
| institution | Directory Open Access Journal |
| issn | 2360-2554 |
| language | English |
| last_indexed | 2024-12-11T14:41:23Z |
| publishDate | 2017-05-01 |
| publisher | Romanian Foundation for Business Intelligence |
| record_format | Article |
| series | SEA: Practical Application of Science |
| spelling | doaj.art-1a5638959e584a66bab0a50b075d258d2022-12-22T01:01:53ZengRomanian Foundation for Business IntelligenceSEA: Practical Application of Science2360-25542017-05-01V13 (1/2017)151156seapas:y:2017:i:13:p:151-156ANALYSIS OF POSSIBLE POSITIVE EFFECTS OF OXYTOCIN ADMINISTERED DURING BIRTH ON THE NEUROMOTOR DEVELOPMENT OF THE 0 - 5 YEAR-OLD-CHILDRENIulia Elena DIACONU0Carmen Rodica ANTON1Emil ANTON2Dumitru FILIPEANU3 The Rehabilitation Hospital of Iaşi, The Neurology Clinic "Gr.T. Popa" University of Medicine and Pharmacy of Iaşi "Gr.T. Popa" University of Medicine and Pharmacy of Iaşi Techical University Gh.Asachi Iasi, Romania Neuropeptide oxytocin (OT) receives increasing attention since, it plays a role in various behaviors including anxiety, drug addiction, learning, social recognition, empathy, pair bonding and decreased aggression. The central nucleus of the amygdala (CeA), part of the limbic system, plays an important role in learning, memory, anxiety and reinforcing mechanisms. Oxytocin receptors are found in the tissues of the cardiovascular system, reproductive system, brain, and are activated by exposure to specific stimuli. The bestknown stimuli related to reproduction are sucking, birth, cervical stimulation during sexual intercourse. Changes in the oxytocinergic system play a fundamental role in the development of autism, mental disorders, including eating disorders, obsessive-compulsive disorder, schizophrenia, with direct impact on the patient’s cognition and social behavior. Some researchers have observed that intranasal Oxytocin (OT) is a potential treatment for multiple neuropsychiatric disorders. As oxytocin is a peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies. Although studies have shown increased cerebrospinal fluid oxytocin levels following intranasal administration, this does not unequivocably demonstrate that the peripherally administered oxytocin is entering the cerebrospinal fluid. For example, it has been suggested that peripheral delivery of oxytocin could lead to central release of endogenous oxytocin. It is also unknown whether the intranasal route provides for more efficient entry of the peptide into the CSF compared to the intravenous (IV) route, which requires blood–brain barrier penetration. http://seaopenresearch.eu/Journals/articles/SPAS_13_18.pdf Oxytocin OTMotor reflexesPsychomotor developmentIntranasal oxytocinOxytocin possible positive effects Neuropsychiatric disorders |
| spellingShingle | Iulia Elena DIACONU Carmen Rodica ANTON Emil ANTON Dumitru FILIPEANU ANALYSIS OF POSSIBLE POSITIVE EFFECTS OF OXYTOCIN ADMINISTERED DURING BIRTH ON THE NEUROMOTOR DEVELOPMENT OF THE 0 - 5 YEAR-OLD-CHILDREN SEA: Practical Application of Science Oxytocin OT Motor reflexes Psychomotor development Intranasal oxytocin Oxytocin possible positive effects Neuropsychiatric disorders |
| title | ANALYSIS OF POSSIBLE POSITIVE EFFECTS OF OXYTOCIN ADMINISTERED DURING BIRTH ON THE NEUROMOTOR DEVELOPMENT OF THE 0 - 5 YEAR-OLD-CHILDREN |
| title_full | ANALYSIS OF POSSIBLE POSITIVE EFFECTS OF OXYTOCIN ADMINISTERED DURING BIRTH ON THE NEUROMOTOR DEVELOPMENT OF THE 0 - 5 YEAR-OLD-CHILDREN |
| title_fullStr | ANALYSIS OF POSSIBLE POSITIVE EFFECTS OF OXYTOCIN ADMINISTERED DURING BIRTH ON THE NEUROMOTOR DEVELOPMENT OF THE 0 - 5 YEAR-OLD-CHILDREN |
| title_full_unstemmed | ANALYSIS OF POSSIBLE POSITIVE EFFECTS OF OXYTOCIN ADMINISTERED DURING BIRTH ON THE NEUROMOTOR DEVELOPMENT OF THE 0 - 5 YEAR-OLD-CHILDREN |
| title_short | ANALYSIS OF POSSIBLE POSITIVE EFFECTS OF OXYTOCIN ADMINISTERED DURING BIRTH ON THE NEUROMOTOR DEVELOPMENT OF THE 0 - 5 YEAR-OLD-CHILDREN |
| title_sort | analysis of possible positive effects of oxytocin administered during birth on the neuromotor development of the 0 5 year old children |
| topic | Oxytocin OT Motor reflexes Psychomotor development Intranasal oxytocin Oxytocin possible positive effects Neuropsychiatric disorders |
| url |
http://seaopenresearch.eu/Journals/articles/SPAS_13_18.pdf
|
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