Hippocampal sleep features: relations to human memory function
The recent spread of intracranial EEG recordings techniques for presurgical evaluation of drug-resistant epileptic patients is providing new information on the activity of different brain structures during both wakefulness and sleep. The interest has been mainly focused on the medial temporal lobe,...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2012-04-01
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| Series: | Frontiers in Neurology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00057/full |
| _version_ | 1818981318344572928 |
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| author | Michele eFerrara Fabio eMoroni Fabio eMoroni Luigi eDe Gennaro Lino eNobili |
| author_facet | Michele eFerrara Fabio eMoroni Fabio eMoroni Luigi eDe Gennaro Lino eNobili |
| author_sort | Michele eFerrara |
| collection | DOAJ |
| description | The recent spread of intracranial EEG recordings techniques for presurgical evaluation of drug-resistant epileptic patients is providing new information on the activity of different brain structures during both wakefulness and sleep. The interest has been mainly focused on the medial temporal lobe, and in particular the hippocampal formation, whose peculiar local sleep features have been recently described, providing support to the idea that sleep is not a spatially global phenomenon. The study of the hippocampal sleep electrophysiology is particularly interesting because of its central role in the declarative memory formation. Recent data indicate that sleep contributes to memory formation. Therefore, it is relevant to understand whether specific pattern of activity taking place during sleep are related to memory consolidation processes. Fascinating similarities between different states of consciousness (wakefulness, REM sleep, NREM sleep) in some electrophysiological mechanisms underlying cognitive processes have been reported. For instance, large-scale synchrony in gamma activity is important for waking memory and perception processes, and its changes during sleep may be the neurophysiological substrate of sleep-related deficits of declarative memory. Hippocampal activity seems to specifically support memory consolidation during sleep, through specific coordinated neurophysiological events (slow waves, spindles, ripples) that would facilitate the integration of new information into the pre-existing cortical networks. A few studies indeed provided direct evidence that rhinal ripples as well as slow hippocampal oscillations are correlated with memory consolidation in humans. More detailed electrophysiological investigations assessing the specific relations between different types of memory consolidation and hippocampal EEG features are in order. These studies will add an important piece of knowledge to the elucidation of the ultimate sleep function. |
| first_indexed | 2024-12-20T17:29:25Z |
| format | Article |
| id | doaj.art-1a587c422da64461846cfa66ac60caa8 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-20T17:29:25Z |
| publishDate | 2012-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-1a587c422da64461846cfa66ac60caa82022-12-21T19:31:26ZengFrontiers Media S.A.Frontiers in Neurology1664-22952012-04-01310.3389/fneur.2012.0005719129Hippocampal sleep features: relations to human memory functionMichele eFerrara0Fabio eMoroni1Fabio eMoroni2Luigi eDe Gennaro3Lino eNobili4University of L'Aquila“Sapienza” University of RomeUniversity of Bologna“Sapienza” University of RomeNiguarda HospitalThe recent spread of intracranial EEG recordings techniques for presurgical evaluation of drug-resistant epileptic patients is providing new information on the activity of different brain structures during both wakefulness and sleep. The interest has been mainly focused on the medial temporal lobe, and in particular the hippocampal formation, whose peculiar local sleep features have been recently described, providing support to the idea that sleep is not a spatially global phenomenon. The study of the hippocampal sleep electrophysiology is particularly interesting because of its central role in the declarative memory formation. Recent data indicate that sleep contributes to memory formation. Therefore, it is relevant to understand whether specific pattern of activity taking place during sleep are related to memory consolidation processes. Fascinating similarities between different states of consciousness (wakefulness, REM sleep, NREM sleep) in some electrophysiological mechanisms underlying cognitive processes have been reported. For instance, large-scale synchrony in gamma activity is important for waking memory and perception processes, and its changes during sleep may be the neurophysiological substrate of sleep-related deficits of declarative memory. Hippocampal activity seems to specifically support memory consolidation during sleep, through specific coordinated neurophysiological events (slow waves, spindles, ripples) that would facilitate the integration of new information into the pre-existing cortical networks. A few studies indeed provided direct evidence that rhinal ripples as well as slow hippocampal oscillations are correlated with memory consolidation in humans. More detailed electrophysiological investigations assessing the specific relations between different types of memory consolidation and hippocampal EEG features are in order. These studies will add an important piece of knowledge to the elucidation of the ultimate sleep function.http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00057/fullHippocampusoscillationsmemory consolidationbrain rhythmsLocal sleepstereo-EEG |
| spellingShingle | Michele eFerrara Fabio eMoroni Fabio eMoroni Luigi eDe Gennaro Lino eNobili Hippocampal sleep features: relations to human memory function Frontiers in Neurology Hippocampus oscillations memory consolidation brain rhythms Local sleep stereo-EEG |
| title | Hippocampal sleep features: relations to human memory function |
| title_full | Hippocampal sleep features: relations to human memory function |
| title_fullStr | Hippocampal sleep features: relations to human memory function |
| title_full_unstemmed | Hippocampal sleep features: relations to human memory function |
| title_short | Hippocampal sleep features: relations to human memory function |
| title_sort | hippocampal sleep features relations to human memory function |
| topic | Hippocampus oscillations memory consolidation brain rhythms Local sleep stereo-EEG |
| url | http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00057/full |
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