Early oseltamivir reduces risk for influenza-associated aspergillosis in a double-hit murine model

Early oseltamivir reduces risk for influenza-associated aspergillosis in a double-hit murine model

Invasive pulmonary aspergillosis (IPA) is a life-threatening fungal infection occurring mainly in immunocompromised patients. We recently identified IPA as an emerging co-infection with high mortality in critically ill, but otherwise immunocompetent influenza patients. The neuraminidase inhibitor os...

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Bibliographic Details
Main Authors: Laura Seldeslachts, Lore Vanderbeke, Astrid Fremau, Agustin Reséndiz-Sharpe, Cato Jacobs, Bo Laeveren, Tessa Ostyn, Lieve Naesens, Matthias Brock, Frank L. Van De Veerdonk, Stephanie Humblet-Baron, Erik Verbeken, Katrien Lagrou, Joost Wauters, Greetje Vande Velde
Format: Article
Language:English
Published: Taylor & Francis Group 2021-12-01
Series:Virulence
Subjects:
influenza-associated pulmonary aspergillosis
oseltamivir
multimodal preclinical imaging-supported mouse model
aspergillus fumigatus
influenza
Online Access:http://dx.doi.org/10.1080/21505594.2021.1974327

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