Modeling and analysis of the molecular basis of pain in sensory neurons.

Modeling and analysis of the molecular basis of pain in sensory neurons.

Intracellular calcium dynamics are critical to cellular functions like pain transmission. Extracellular ATP plays an important role in modulating intracellular calcium levels by interacting with the P2 family of surface receptors. In this study, we developed a mechanistic mathematical model of ATP-i...

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Bibliographic Details
Main Authors: Sang Ok Song, Jeffrey Varner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2735677?pdf=render

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