Enhancing immunogenicity of novel multistage subunit vaccine of Mycobacterium tuberculosis using PLGA:DDA hybrid nanoparticles and MPLA : subcutaneous administration

Enhancing immunogenicity of novel multistage subunit vaccine of Mycobacterium tuberculosis using PLGA:DDA hybrid nanoparticles and MPLA : subcutaneous administration

Objective(s): A new strategy in recent studies is using effective tuberculosis (TB) subunit vaccines combined with appropriate carriers and adjuvants which have shown promising results in preclinical and clinical studies. The aim of the present study was to evaluate the PLGA:DDA hybrid nanoparticles...

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Bibliographic Details
Main Authors: Farzad Khademi, Arshid Yousefi, Mohammad Derakhshan, Adel Najafi, Mohsen Tafaghodi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2019-08-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Mycobacterium tuberculosis
Multistage subunit vaccine
PLGA:DDA nanoparticle
MPLA
Immunization
Online Access:http://ijbms.mums.ac.ir/article_13321_066c72f5407dd8f47bd090c7d1a9a493.pdf

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