Advances in research to restore vision
Mammalian eyes have a limited ability to regenerate once neurons degenerate. This results in visual impairment that impacts the quality of life among adult populations as well as in young children leading to lifelong consequences. Various therapies are in development to restore vision, and these inc...
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| Format: | Article |
| Language: | English |
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The Korean Society of Animal Reproduction and Biotechnology
2023-03-01
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| Series: | Journal of Animal Reproduction and Biotechnology |
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| Online Access: | https://www.e-jarb.org/journal/view.html?uid=2647&vmd=Full |
| _version_ | 1797854782327619584 |
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| author | Kun Do Rhee |
| author_facet | Kun Do Rhee |
| author_sort | Kun Do Rhee |
| collection | DOAJ |
| description | Mammalian eyes have a limited ability to regenerate once neurons degenerate. This results in visual impairment that impacts the quality of life among adult populations as well as in young children leading to lifelong consequences. Various therapies are in development to restore vision, and these include gene therapy, stem cell therapy, in-vivo transdifferentiation, and transplantation of a patient’s whole eye obtained from interspecies blastocyst complementation. This review discusses advances in the research as well as hurdles that need to be resolved to have a successful restoration of vision. |
| first_indexed | 2024-04-09T20:12:49Z |
| format | Article |
| id | doaj.art-1a60d745f0864fb78cce84984bb09ba0 |
| institution | Directory Open Access Journal |
| issn | 2671-4639 2671-4663 |
| language | English |
| last_indexed | 2024-04-09T20:12:49Z |
| publishDate | 2023-03-01 |
| publisher | The Korean Society of Animal Reproduction and Biotechnology |
| record_format | Article |
| series | Journal of Animal Reproduction and Biotechnology |
| spelling | doaj.art-1a60d745f0864fb78cce84984bb09ba02023-03-31T15:00:45ZengThe Korean Society of Animal Reproduction and BiotechnologyJournal of Animal Reproduction and Biotechnology2671-46392671-46632023-03-013812910.12750/JARB.38.1.2Advances in research to restore visionKun Do Rhee0https://orcid.org/0000-0003-2886-468XChangpa Institute, Daegu University, Gyeongsan 38453, KoreaMammalian eyes have a limited ability to regenerate once neurons degenerate. This results in visual impairment that impacts the quality of life among adult populations as well as in young children leading to lifelong consequences. Various therapies are in development to restore vision, and these include gene therapy, stem cell therapy, in-vivo transdifferentiation, and transplantation of a patient’s whole eye obtained from interspecies blastocyst complementation. This review discusses advances in the research as well as hurdles that need to be resolved to have a successful restoration of vision.https://www.e-jarb.org/journal/view.html?uid=2647&vmd=Fullblastocyst complementationgene therapyregenerative medicineretinal regenerationreprogramming |
| spellingShingle | Kun Do Rhee Advances in research to restore vision Journal of Animal Reproduction and Biotechnology blastocyst complementation gene therapy regenerative medicine retinal regeneration reprogramming |
| title | Advances in research to restore vision |
| title_full | Advances in research to restore vision |
| title_fullStr | Advances in research to restore vision |
| title_full_unstemmed | Advances in research to restore vision |
| title_short | Advances in research to restore vision |
| title_sort | advances in research to restore vision |
| topic | blastocyst complementation gene therapy regenerative medicine retinal regeneration reprogramming |
| url | https://www.e-jarb.org/journal/view.html?uid=2647&vmd=Full |
| work_keys_str_mv | AT kundorhee advancesinresearchtorestorevision |