The impact of vaccine-linked chemotherapy on liver health in a mouse model of chronic Trypanosoma cruzi infection.
<h4>Background</h4>Chagas disease, chronic infection with Trypanosoma cruzi, mainly manifests as cardiac disease. However, the liver is important for both controlling parasite burdens and metabolizing drugs. Notably, high doses of anti-parasitic drug benznidazole (BNZ) causes liver damag...
Main Authors: | Duc Minh Nguyen, Cristina Poveda, Jeroen Pollet, Fabian Gusovsky, Maria Elena Bottazzi, Peter J Hotez, Kathryn Marie Jones |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-11-01
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Series: | PLoS Neglected Tropical Diseases |
Online Access: | https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011519&type=printable |
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