The mechanical property and corrosion resistance of Mg-Zn-Nd alloy fine wires in vitro and in vivo
Titanium and its alloy are commonly used as surgical staples in the reconstruction of intestinal tract and stomach, however they cannot be absorbed in human body, which may cause a series of complications to influence further diagnosis. Magnesium and its alloy have great potential as surgical staple...
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| Format: | Article |
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KeAi Communications Co., Ltd.
2021-01-01
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| Series: | Bioactive Materials |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X20301389 |
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| author | Ming Gao Di Na Xiangqiao Ni Lihui Song Iniobong P. Etim Ke Yang Lili Tan Zheng Ma |
| author_facet | Ming Gao Di Na Xiangqiao Ni Lihui Song Iniobong P. Etim Ke Yang Lili Tan Zheng Ma |
| author_sort | Ming Gao |
| collection | DOAJ |
| description | Titanium and its alloy are commonly used as surgical staples in the reconstruction of intestinal tract and stomach, however they cannot be absorbed in human body, which may cause a series of complications to influence further diagnosis. Magnesium and its alloy have great potential as surgical staples, because they can be degraded in human body and have good mechanical properties and biocompatibility. In this study, Mg-2Zn-0.5Nd (ZN20) alloy fine wires showed great potential as surgical staples. The ultimate tensile strength and elongation of ZN20 alloy fine wires were 248 MPa and 13%, respectively, which could be benefit for the deformation of the surgical staples from U-shape to B-shape. The bursting pressure of the wire was about 40 kPa, implying that it can supply sufficient mechanical support after anastomosis. Biochemical test and histological analysis illustrated good biocompatibility and biological safety of ZN20 alloy fine wire. The residual tensile stress formed on the outside of ZN20 fine wire during drawing would accelerate the corrosion. The second phase had a negative influence on corrosion property due to galvanic corrosion. The corrosion rate in vitro was faster than that in vivo due to the capsule formed on the surface of ZN20 alloy fine wire. |
| first_indexed | 2024-04-24T08:50:40Z |
| format | Article |
| id | doaj.art-1a69f77ea7f84a928598b1bfc2cbec4c |
| institution | Directory Open Access Journal |
| issn | 2452-199X |
| language | English |
| last_indexed | 2024-04-24T08:50:40Z |
| publishDate | 2021-01-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Bioactive Materials |
| spelling | doaj.art-1a69f77ea7f84a928598b1bfc2cbec4c2024-04-16T11:54:04ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2021-01-01615563The mechanical property and corrosion resistance of Mg-Zn-Nd alloy fine wires in vitro and in vivoMing Gao0Di Na1Xiangqiao Ni2Lihui Song3Iniobong P. Etim4Ke Yang5Lili Tan6Zheng Ma7School of Materials Science and Engineering, University of Science and Technology of China, Shenyang, 110016, China; Institute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, ChinaThe First Hospital of China Medical University, Department of Surgical Oncology, ChinaThe First Hospital of China Medical University, Department of Surgical Oncology, ChinaThe First Hospital of China Medical University, Department of Surgical Oncology, ChinaSchool of Materials Science and Engineering, University of Science and Technology of China, Shenyang, 110016, China; Institute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, ChinaInstitute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, China; Corresponding author. 72 Wenhua Road, Shenyang, Liaoning, 110016, China.Institute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, China; Corresponding author.Titanium and its alloy are commonly used as surgical staples in the reconstruction of intestinal tract and stomach, however they cannot be absorbed in human body, which may cause a series of complications to influence further diagnosis. Magnesium and its alloy have great potential as surgical staples, because they can be degraded in human body and have good mechanical properties and biocompatibility. In this study, Mg-2Zn-0.5Nd (ZN20) alloy fine wires showed great potential as surgical staples. The ultimate tensile strength and elongation of ZN20 alloy fine wires were 248 MPa and 13%, respectively, which could be benefit for the deformation of the surgical staples from U-shape to B-shape. The bursting pressure of the wire was about 40 kPa, implying that it can supply sufficient mechanical support after anastomosis. Biochemical test and histological analysis illustrated good biocompatibility and biological safety of ZN20 alloy fine wire. The residual tensile stress formed on the outside of ZN20 fine wire during drawing would accelerate the corrosion. The second phase had a negative influence on corrosion property due to galvanic corrosion. The corrosion rate in vitro was faster than that in vivo due to the capsule formed on the surface of ZN20 alloy fine wire.http://www.sciencedirect.com/science/article/pii/S2452199X20301389MagnesiumSurgical stapleAnastomosisCorrosion resistanceIn vivo |
| spellingShingle | Ming Gao Di Na Xiangqiao Ni Lihui Song Iniobong P. Etim Ke Yang Lili Tan Zheng Ma The mechanical property and corrosion resistance of Mg-Zn-Nd alloy fine wires in vitro and in vivo Bioactive Materials Magnesium Surgical staple Anastomosis Corrosion resistance In vivo |
| title | The mechanical property and corrosion resistance of Mg-Zn-Nd alloy fine wires in vitro and in vivo |
| title_full | The mechanical property and corrosion resistance of Mg-Zn-Nd alloy fine wires in vitro and in vivo |
| title_fullStr | The mechanical property and corrosion resistance of Mg-Zn-Nd alloy fine wires in vitro and in vivo |
| title_full_unstemmed | The mechanical property and corrosion resistance of Mg-Zn-Nd alloy fine wires in vitro and in vivo |
| title_short | The mechanical property and corrosion resistance of Mg-Zn-Nd alloy fine wires in vitro and in vivo |
| title_sort | mechanical property and corrosion resistance of mg zn nd alloy fine wires in vitro and in vivo |
| topic | Magnesium Surgical staple Anastomosis Corrosion resistance In vivo |
| url | http://www.sciencedirect.com/science/article/pii/S2452199X20301389 |
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