Comparison of Adverse Events of Different Endoscopic Ultrasound-Guided Tissue Acquisition Methods: A Single-Center Retrospective Analysis
The efficacy of new generation endoscopic ultrasound-guided biopsy needles has been promising in recent years. Yet, comparing these needles’ diagnostic yield and safety to conventional needles is not well-known. Our study aims to compare the adverse events of endoscopic ultrasound-guided tissue acqu...
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| Format: | Article |
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MDPI AG
2022-09-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/9/2123 |
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| author | Yen-Chih Lin Hsu-Heng Yen Siou-Ping Huang Kai-Lun Shih Yang-Yuan Chen |
| author_facet | Yen-Chih Lin Hsu-Heng Yen Siou-Ping Huang Kai-Lun Shih Yang-Yuan Chen |
| author_sort | Yen-Chih Lin |
| collection | DOAJ |
| description | The efficacy of new generation endoscopic ultrasound-guided biopsy needles has been promising in recent years. Yet, comparing these needles’ diagnostic yield and safety to conventional needles is not well-known. Our study aims to compare the adverse events of endoscopic ultrasound-guided tissue acquisition (EUS-TA) with different types of needles, including FNA needles, FNB needles with a Franseen tip and FNB needles with a reverse bevel. Furthermore, we will analyze the risk factors, including tumor vascularity, different needle types, and the underlying disease, which may impact the safety of the procedures. From May 2014 to December 2021, 192 consecutive EUS-TAs were performed on pancreatic and peripancreatic lesions in our hospital using different types of FNA and FNB needles. We retrospectively reviewed the data and identified the risk factors for EUS-TA-related complications. As a result, the hypervascular tumor is a significant risk factor for adverse events in our multivariate analysis, with an odds ratio of 4.96 (95% CI 1.33–18.47), while liver cirrhosis is one of the risk factors for adverse events during EUS-TA, with an odds ratio of 5.3 (95% CI 1.1–25.6). However, the risk of adverse events did not increase using Franseen-tip needles, compared to conventional FNA or FNB needles with a reverse bevel. In conclusion, we must be more cautious in patients with liver cirrhosis and hypervascular tumors, such as pancreatic neuroendocrine tumors, when performing EUS-guided tissue acquisition. |
| first_indexed | 2024-03-10T00:16:38Z |
| format | Article |
| id | doaj.art-1a70c46e3a9d4bec9476d981ba7e7a46 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T00:16:38Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-1a70c46e3a9d4bec9476d981ba7e7a462023-11-23T15:49:06ZengMDPI AGDiagnostics2075-44182022-09-01129212310.3390/diagnostics12092123Comparison of Adverse Events of Different Endoscopic Ultrasound-Guided Tissue Acquisition Methods: A Single-Center Retrospective AnalysisYen-Chih Lin0Hsu-Heng Yen1Siou-Ping Huang2Kai-Lun Shih3Yang-Yuan Chen4Division of Gastroenterology, Changhua Christian Hospital, Changhua 500, TaiwanDivision of Gastroenterology, Changhua Christian Hospital, Changhua 500, TaiwanDivision of Gastroenterology, Changhua Christian Hospital, Changhua 500, TaiwanDivision of Gastroenterology, Changhua Christian Hospital, Changhua 500, TaiwanDivision of Gastroenterology, Changhua Christian Hospital, Changhua 500, TaiwanThe efficacy of new generation endoscopic ultrasound-guided biopsy needles has been promising in recent years. Yet, comparing these needles’ diagnostic yield and safety to conventional needles is not well-known. Our study aims to compare the adverse events of endoscopic ultrasound-guided tissue acquisition (EUS-TA) with different types of needles, including FNA needles, FNB needles with a Franseen tip and FNB needles with a reverse bevel. Furthermore, we will analyze the risk factors, including tumor vascularity, different needle types, and the underlying disease, which may impact the safety of the procedures. From May 2014 to December 2021, 192 consecutive EUS-TAs were performed on pancreatic and peripancreatic lesions in our hospital using different types of FNA and FNB needles. We retrospectively reviewed the data and identified the risk factors for EUS-TA-related complications. As a result, the hypervascular tumor is a significant risk factor for adverse events in our multivariate analysis, with an odds ratio of 4.96 (95% CI 1.33–18.47), while liver cirrhosis is one of the risk factors for adverse events during EUS-TA, with an odds ratio of 5.3 (95% CI 1.1–25.6). However, the risk of adverse events did not increase using Franseen-tip needles, compared to conventional FNA or FNB needles with a reverse bevel. In conclusion, we must be more cautious in patients with liver cirrhosis and hypervascular tumors, such as pancreatic neuroendocrine tumors, when performing EUS-guided tissue acquisition.https://www.mdpi.com/2075-4418/12/9/2123endoscopic ultrasoundpancreatic diseasefine needle biopsy |
| spellingShingle | Yen-Chih Lin Hsu-Heng Yen Siou-Ping Huang Kai-Lun Shih Yang-Yuan Chen Comparison of Adverse Events of Different Endoscopic Ultrasound-Guided Tissue Acquisition Methods: A Single-Center Retrospective Analysis Diagnostics endoscopic ultrasound pancreatic disease fine needle biopsy |
| title | Comparison of Adverse Events of Different Endoscopic Ultrasound-Guided Tissue Acquisition Methods: A Single-Center Retrospective Analysis |
| title_full | Comparison of Adverse Events of Different Endoscopic Ultrasound-Guided Tissue Acquisition Methods: A Single-Center Retrospective Analysis |
| title_fullStr | Comparison of Adverse Events of Different Endoscopic Ultrasound-Guided Tissue Acquisition Methods: A Single-Center Retrospective Analysis |
| title_full_unstemmed | Comparison of Adverse Events of Different Endoscopic Ultrasound-Guided Tissue Acquisition Methods: A Single-Center Retrospective Analysis |
| title_short | Comparison of Adverse Events of Different Endoscopic Ultrasound-Guided Tissue Acquisition Methods: A Single-Center Retrospective Analysis |
| title_sort | comparison of adverse events of different endoscopic ultrasound guided tissue acquisition methods a single center retrospective analysis |
| topic | endoscopic ultrasound pancreatic disease fine needle biopsy |
| url | https://www.mdpi.com/2075-4418/12/9/2123 |
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