Effect of method of deduplication on estimation of differential gene expression using RNA-seq
Background RNA-seq is a useful tool for analysis of gene expression. However, its robustness is greatly affected by a number of artifacts. One of them is the presence of duplicated reads. Results To infer the influence of different methods of removal of duplicated reads on estimation of gene express...
Main Authors: | Anna V. Klepikova, Artem S. Kasianov, Mikhail S. Chesnokov, Natalia L. Lazarevich, Aleksey A. Penin, Maria Logacheva |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-03-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/3091.pdf |
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