Adaptation of African swine fever virus to porcine kidney cells stably expressing CD163 and Siglec1

Adaptation of African swine fever virus to porcine kidney cells stably expressing CD163 and Siglec1

African swine fever virus (ASFV) is a complex large DNA enveloped virus that causes African swine fever (ASF) with a fatality rate of up to 100%, seriously threatening the global swine industry. Due to the strict cell tropism of ASFV, there is no effective in vitro cell line, which hinders its preve...

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Bibliographic Details
Main Authors: Qi Gao, Yunlong Yang, Yizhuo Luo, Jiachen Zheng, Lang Gong, Heng Wang, Yongzhi Feng, Ting Gong, Dongdong Wu, Ruixia Wu, Xiaoyu Zheng, Zezhong Zheng, Guihong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
African swine fever virus
whole gene transcription
adaptation
CD163
Siglec1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1015224/full

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