Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study
Eivind Schjelderup Skarpsno,1,2 Paul Jarle Mork,1 Knut Hagen,3,4 Tom Ivar Lund Nilsen,1,5 Anna Marcuzzi1 1Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; 2Department of Neurology and Clinical Neurophysiology, St. Olavs Hospital, Tron...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2020-12-01
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| Series: | Nature and Science of Sleep |
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| Online Access: | https://www.dovepress.com/number-of-chronic-nighttime-insomnia-symptoms-and-risk-of-chronic-wide-peer-reviewed-article-NSS |
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| author | Skarpsno ES Mork PJ Hagen K Nilsen TIL Marcuzzi A |
| author_facet | Skarpsno ES Mork PJ Hagen K Nilsen TIL Marcuzzi A |
| author_sort | Skarpsno ES |
| collection | DOAJ |
| description | Eivind Schjelderup Skarpsno,1,2 Paul Jarle Mork,1 Knut Hagen,3,4 Tom Ivar Lund Nilsen,1,5 Anna Marcuzzi1 1Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; 2Department of Neurology and Clinical Neurophysiology, St. Olavs Hospital, Trondheim, Norway; 3Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; 4Clinical Research Unit Central Norway, St. Olavs Hospital, Trondheim, Norway; 5Clinic of Anaesthesia and Intensive Care, St. Olavs Hospital, Trondheim University Hospital, Trondheim, NorwayCorrespondence: Eivind Schjelderup SkarpsnoDepartment of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Håkon Jarls Gate 11, Samfunnsmedisinbygget, Trondheim 7030, NorwayTel +47 97521297Email eivind.s.skarpsno@ntnu.noStudy Objectives: To examine the association between the number of chronic nighttime insomnia symptoms and the risk of chronic widespread pain (CWP) and pain-related disability.Methods: A prospective study of 10,847 participants in the Norwegian HUNT Study without chronic musculoskeletal pain at baseline in 2006– 2008. We used a modified Poisson regression model to estimate adjusted risk ratios (RRs) with a 95% confidence interval (CI) for CWP and pain-related disability at follow-up in 2017– 2019 associated with insomnia and number of nighttime insomnia symptoms at baseline. Chronic insomnia was defined according to the current classification system and grouped into three categories based on the number of reported nighttime symptoms (ie, difficulty initiating sleep, trouble maintaining sleep and early morning awakenings).Results: Compared to the reference group of people without insomnia, people with insomnia had RRs for CWP and pain-related disability of 1.64 (1.26– 2.14) and 1.63 (1.37– 1.94), respectively. When people with insomnia were categorized based on the number of nighttime symptoms, people who reported one, two, or three nighttime symptoms had RRs of CWP of 1.19 (95% CI 0.80– 1.78), 1.78 (95 CI 1.13– 2.80) and 3.08 (95% CI 1.93– 4.92), respectively, compared to people without insomnia. The corresponding RRs for pain-related disability were 1.49 (95% CI 1.17– 1.89), 1.46 (95% CI 2.04– 2.05), and 2.46 (95% CI 1.76– 3.42).Conclusion: These findings indicate that people with insomnia characterized by symptoms in all phases of the sleep period have a substantially increased risk of CWP and pain-related disability.Keywords: sleeplessness, insomnia disorder, chronic insomnia, musculoskeletal, pain, chronic, widespread chronic pain, relative risk, epidemiology |
| first_indexed | 2024-12-18T04:21:08Z |
| format | Article |
| id | doaj.art-1a774058703047a2878c101e9e4ce619 |
| institution | Directory Open Access Journal |
| issn | 1179-1608 |
| language | English |
| last_indexed | 2024-12-18T04:21:08Z |
| publishDate | 2020-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Nature and Science of Sleep |
| spelling | doaj.art-1a774058703047a2878c101e9e4ce6192022-12-21T21:21:14ZengDove Medical PressNature and Science of Sleep1179-16082020-12-01Volume 121227123660716Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT StudySkarpsno ESMork PJHagen KNilsen TILMarcuzzi AEivind Schjelderup Skarpsno,1,2 Paul Jarle Mork,1 Knut Hagen,3,4 Tom Ivar Lund Nilsen,1,5 Anna Marcuzzi1 1Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; 2Department of Neurology and Clinical Neurophysiology, St. Olavs Hospital, Trondheim, Norway; 3Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; 4Clinical Research Unit Central Norway, St. Olavs Hospital, Trondheim, Norway; 5Clinic of Anaesthesia and Intensive Care, St. Olavs Hospital, Trondheim University Hospital, Trondheim, NorwayCorrespondence: Eivind Schjelderup SkarpsnoDepartment of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Håkon Jarls Gate 11, Samfunnsmedisinbygget, Trondheim 7030, NorwayTel +47 97521297Email eivind.s.skarpsno@ntnu.noStudy Objectives: To examine the association between the number of chronic nighttime insomnia symptoms and the risk of chronic widespread pain (CWP) and pain-related disability.Methods: A prospective study of 10,847 participants in the Norwegian HUNT Study without chronic musculoskeletal pain at baseline in 2006– 2008. We used a modified Poisson regression model to estimate adjusted risk ratios (RRs) with a 95% confidence interval (CI) for CWP and pain-related disability at follow-up in 2017– 2019 associated with insomnia and number of nighttime insomnia symptoms at baseline. Chronic insomnia was defined according to the current classification system and grouped into three categories based on the number of reported nighttime symptoms (ie, difficulty initiating sleep, trouble maintaining sleep and early morning awakenings).Results: Compared to the reference group of people without insomnia, people with insomnia had RRs for CWP and pain-related disability of 1.64 (1.26– 2.14) and 1.63 (1.37– 1.94), respectively. When people with insomnia were categorized based on the number of nighttime symptoms, people who reported one, two, or three nighttime symptoms had RRs of CWP of 1.19 (95% CI 0.80– 1.78), 1.78 (95 CI 1.13– 2.80) and 3.08 (95% CI 1.93– 4.92), respectively, compared to people without insomnia. The corresponding RRs for pain-related disability were 1.49 (95% CI 1.17– 1.89), 1.46 (95% CI 2.04– 2.05), and 2.46 (95% CI 1.76– 3.42).Conclusion: These findings indicate that people with insomnia characterized by symptoms in all phases of the sleep period have a substantially increased risk of CWP and pain-related disability.Keywords: sleeplessness, insomnia disorder, chronic insomnia, musculoskeletal, pain, chronic, widespread chronic pain, relative risk, epidemiologyhttps://www.dovepress.com/number-of-chronic-nighttime-insomnia-symptoms-and-risk-of-chronic-wide-peer-reviewed-article-NSSsleeplessnessinsomnia disorderchronic insomniamusculoskeletalpainchronicwidespread chronic painrelative riskepidemiology |
| spellingShingle | Skarpsno ES Mork PJ Hagen K Nilsen TIL Marcuzzi A Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study Nature and Science of Sleep sleeplessness insomnia disorder chronic insomnia musculoskeletal pain chronic widespread chronic pain relative risk epidemiology |
| title | Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study |
| title_full | Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study |
| title_fullStr | Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study |
| title_full_unstemmed | Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study |
| title_short | Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study |
| title_sort | number of chronic nighttime insomnia symptoms and risk of chronic widespread pain and pain related disability the hunt study |
| topic | sleeplessness insomnia disorder chronic insomnia musculoskeletal pain chronic widespread chronic pain relative risk epidemiology |
| url | https://www.dovepress.com/number-of-chronic-nighttime-insomnia-symptoms-and-risk-of-chronic-wide-peer-reviewed-article-NSS |
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