Screening and characterization of inhibitory vNAR targeting nanodisc-assembled influenza M2 proteins

Screening and characterization of inhibitory vNAR targeting nanodisc-assembled influenza M2 proteins

Summary: Influenza A virus poses a constant challenge to human health. The highly conserved influenza matrix-2 (M2) protein is an attractive target for the development of a universal antibody-based drug. However, screening using antigens with subphysiological conformation in a nonmembrane environmen...

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Bibliographic Details
Main Authors: Chuandi Yu, Wen Ding, Lei Zhu, Yuhang Zhou, Yingkui Dong, Ling Li, Juanjuan Liu, Yizhuo Wang, Zehua Li, Lina Zhu, FaJun Chen, Maosen Ruan, Dongming Qian, Yujuan Wang, Bo Wu, Huangtao Xu, Ming Li, Yunchen Bi, Hao Wang, Weiqian Wang, Peng Chao, Lei Xing, Bing Shen, Han Dai, Lisha Zha, Hongxin Zhao, Junfeng Wang
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:iScience
Subjects:
Virology
Nanoparticles
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222020090

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http://www.sciencedirect.com/science/article/pii/S2589004222020090

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