Effect of resistance training and high-intensity interval training on metabolic parameters and serum level of Sirtuin1 in postmenopausal women with metabolic syndrome: a randomized controlled trial
Abstract Background The present study analyzes the influence of resistance training (RT) and high-intensity interval training (HIIT) on metabolic indices and serum levels of Sirtuin1 (SIRT1) in postmenopausal women who suffer from the metabolic syndrome (MetS). Methods 45 postmenopausal women aged 4...
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | Lipids in Health and Disease |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12944-023-01940-x |
| _version_ | 1797451667920125952 |
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| author | Saeid Shamlou Kazemi Ali Heidarianpour Elnaz Shokri |
| author_facet | Saeid Shamlou Kazemi Ali Heidarianpour Elnaz Shokri |
| author_sort | Saeid Shamlou Kazemi |
| collection | DOAJ |
| description | Abstract Background The present study analyzes the influence of resistance training (RT) and high-intensity interval training (HIIT) on metabolic indices and serum levels of Sirtuin1 (SIRT1) in postmenopausal women who suffer from the metabolic syndrome (MetS). Methods 45 postmenopausal women aged 45–65 years with MetS were divided into two intervention groups (RT and HIIT) and one control group, each consisting of 15 people. The RT group performed resistance training for both the upper and lower body, while the HIIT group completed 3 min(min) of high-intensity training at 80–90% of their maximum heart rate (HRmax), followed by moderate walking for 3 min at 55–65% of HRmax. These sessions were conducted for a duration of eight weeks and three times a week, with the samples being collected at the baseline and at the end of the treatment, i.e., week 8. Results The results showed that weight, waist circumference, body mass index, fat mass, low-density lipoprotein, triglyceride, cholesterol, fasting blood sugar (FBS), hemoglobin A1c (HbA1C), systolic and diastolic blood pressure decreased, and SIRT1 increased significantly in both training groups. Systolic blood pressure, cholesterol, HbA1C, and FBS decreased more in the HIIT group. Skeletal muscle mass and 1-repetition maximum (1-RM) increased more in the RT group. Conclusions RT and HIIT serve as one of the most effective strategies for therapeutically treating patients with metabolic syndrome. Trial registration IRCT, IRCT20221120056548N1. Registered 23 November 2022 - Retrospectively registered. |
| first_indexed | 2024-03-09T14:56:50Z |
| format | Article |
| id | doaj.art-1a78d3b39f9a466b92ae0a189233e362 |
| institution | Directory Open Access Journal |
| issn | 1476-511X |
| language | English |
| last_indexed | 2024-03-09T14:56:50Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Lipids in Health and Disease |
| spelling | doaj.art-1a78d3b39f9a466b92ae0a189233e3622023-11-26T14:06:00ZengBMCLipids in Health and Disease1476-511X2023-10-0122111110.1186/s12944-023-01940-xEffect of resistance training and high-intensity interval training on metabolic parameters and serum level of Sirtuin1 in postmenopausal women with metabolic syndrome: a randomized controlled trialSaeid Shamlou Kazemi0Ali Heidarianpour1Elnaz Shokri2Faculty of Sport Sciences, Bu-Ali Sina UniversityFaculty of Sport Sciences, Bu-Ali Sina UniversityFaculty of Sport Sciences, Bu-Ali Sina UniversityAbstract Background The present study analyzes the influence of resistance training (RT) and high-intensity interval training (HIIT) on metabolic indices and serum levels of Sirtuin1 (SIRT1) in postmenopausal women who suffer from the metabolic syndrome (MetS). Methods 45 postmenopausal women aged 45–65 years with MetS were divided into two intervention groups (RT and HIIT) and one control group, each consisting of 15 people. The RT group performed resistance training for both the upper and lower body, while the HIIT group completed 3 min(min) of high-intensity training at 80–90% of their maximum heart rate (HRmax), followed by moderate walking for 3 min at 55–65% of HRmax. These sessions were conducted for a duration of eight weeks and three times a week, with the samples being collected at the baseline and at the end of the treatment, i.e., week 8. Results The results showed that weight, waist circumference, body mass index, fat mass, low-density lipoprotein, triglyceride, cholesterol, fasting blood sugar (FBS), hemoglobin A1c (HbA1C), systolic and diastolic blood pressure decreased, and SIRT1 increased significantly in both training groups. Systolic blood pressure, cholesterol, HbA1C, and FBS decreased more in the HIIT group. Skeletal muscle mass and 1-repetition maximum (1-RM) increased more in the RT group. Conclusions RT and HIIT serve as one of the most effective strategies for therapeutically treating patients with metabolic syndrome. Trial registration IRCT, IRCT20221120056548N1. Registered 23 November 2022 - Retrospectively registered.https://doi.org/10.1186/s12944-023-01940-xMetabolic syndromeHigh-intensity interval trainingResistance trainingSirtuin1 |
| spellingShingle | Saeid Shamlou Kazemi Ali Heidarianpour Elnaz Shokri Effect of resistance training and high-intensity interval training on metabolic parameters and serum level of Sirtuin1 in postmenopausal women with metabolic syndrome: a randomized controlled trial Lipids in Health and Disease Metabolic syndrome High-intensity interval training Resistance training Sirtuin1 |
| title | Effect of resistance training and high-intensity interval training on metabolic parameters and serum level of Sirtuin1 in postmenopausal women with metabolic syndrome: a randomized controlled trial |
| title_full | Effect of resistance training and high-intensity interval training on metabolic parameters and serum level of Sirtuin1 in postmenopausal women with metabolic syndrome: a randomized controlled trial |
| title_fullStr | Effect of resistance training and high-intensity interval training on metabolic parameters and serum level of Sirtuin1 in postmenopausal women with metabolic syndrome: a randomized controlled trial |
| title_full_unstemmed | Effect of resistance training and high-intensity interval training on metabolic parameters and serum level of Sirtuin1 in postmenopausal women with metabolic syndrome: a randomized controlled trial |
| title_short | Effect of resistance training and high-intensity interval training on metabolic parameters and serum level of Sirtuin1 in postmenopausal women with metabolic syndrome: a randomized controlled trial |
| title_sort | effect of resistance training and high intensity interval training on metabolic parameters and serum level of sirtuin1 in postmenopausal women with metabolic syndrome a randomized controlled trial |
| topic | Metabolic syndrome High-intensity interval training Resistance training Sirtuin1 |
| url | https://doi.org/10.1186/s12944-023-01940-x |
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