Mesenchymal Lesion in an Adolescent Girl-A Rare Case Report

Rhabdomyosarcoma (RMS) comprises 3% of all childhood malignancy. Commonly it involves head and neck, extremity and genitourinary systems. Pure primary RMS of breast is a rare malignacy. Here, we present a case of adolescent girl presented with breast lump which was initially treated as benign lesion...

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Main Authors: R Manibarathi, R Narmadha, AP Rajesh Nataraj, J Pavithra, Bharathi Vidhya Jayanthi
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2018-03-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/11247/32412_F(SHU)_PF1_(MLS_BT_RA_SHU)_PFA(NC_MLS_SL)_PB(MLS_SL)_PN(SL).pdf
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author R Manibarathi
R Narmadha
AP Rajesh Nataraj
J Pavithra
Bharathi Vidhya Jayanthi
author_facet R Manibarathi
R Narmadha
AP Rajesh Nataraj
J Pavithra
Bharathi Vidhya Jayanthi
author_sort R Manibarathi
collection DOAJ
description Rhabdomyosarcoma (RMS) comprises 3% of all childhood malignancy. Commonly it involves head and neck, extremity and genitourinary systems. Pure primary RMS of breast is a rare malignacy. Here, we present a case of adolescent girl presented with breast lump which was initially treated as benign lesion with excision. Again she presented with recurrent mass which was operated and microscopically showed features of small blue round cell tumour which has lead to many diagnostic confusions both clinically and histopathologically. Immunohistochemistry (IHC) with strong nuclear myogenin positivity in >50% of tumour cells confirms the diagnosis of primary mammary RMS. Postoperative period was uneventful.
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spelling doaj.art-1a7996a9f734492d8d9dd102ca6d4bb42022-12-21T21:18:42ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2018-03-01123ED03ED0510.7860/JCDR/2018/32412.11247Mesenchymal Lesion in an Adolescent Girl-A Rare Case ReportR Manibarathi0R Narmadha1AP Rajesh Nataraj2J Pavithra3Bharathi Vidhya Jayanthi4Postgraduate, Department of Pathology, Madras Medical College, Chennai, Tamil Nadu, India.Assistant Professor, Department of Pathology, Madras Medical College, Chennai, Tamil Nadu, India.Assistant Professor, Department of Pathology, Madras Medical College, Chennai, Tamil Nadu, India.Tutor, Department of Pathology, Madras Medical College, Chennai, Tamil Nadu, India. Director and Professor, Department of Pathology, Madras Medical College, Chennai, Tamil Nadu, India.Rhabdomyosarcoma (RMS) comprises 3% of all childhood malignancy. Commonly it involves head and neck, extremity and genitourinary systems. Pure primary RMS of breast is a rare malignacy. Here, we present a case of adolescent girl presented with breast lump which was initially treated as benign lesion with excision. Again she presented with recurrent mass which was operated and microscopically showed features of small blue round cell tumour which has lead to many diagnostic confusions both clinically and histopathologically. Immunohistochemistry (IHC) with strong nuclear myogenin positivity in >50% of tumour cells confirms the diagnosis of primary mammary RMS. Postoperative period was uneventful.https://jcdr.net/articles/PDF/11247/32412_F(SHU)_PF1_(MLS_BT_RA_SHU)_PFA(NC_MLS_SL)_PB(MLS_SL)_PN(SL).pdfadolescent agemyogeninrhabdomyosarcoma of breast
spellingShingle R Manibarathi
R Narmadha
AP Rajesh Nataraj
J Pavithra
Bharathi Vidhya Jayanthi
Mesenchymal Lesion in an Adolescent Girl-A Rare Case Report
Journal of Clinical and Diagnostic Research
adolescent age
myogenin
rhabdomyosarcoma of breast
title Mesenchymal Lesion in an Adolescent Girl-A Rare Case Report
title_full Mesenchymal Lesion in an Adolescent Girl-A Rare Case Report
title_fullStr Mesenchymal Lesion in an Adolescent Girl-A Rare Case Report
title_full_unstemmed Mesenchymal Lesion in an Adolescent Girl-A Rare Case Report
title_short Mesenchymal Lesion in an Adolescent Girl-A Rare Case Report
title_sort mesenchymal lesion in an adolescent girl a rare case report
topic adolescent age
myogenin
rhabdomyosarcoma of breast
url https://jcdr.net/articles/PDF/11247/32412_F(SHU)_PF1_(MLS_BT_RA_SHU)_PFA(NC_MLS_SL)_PB(MLS_SL)_PN(SL).pdf
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