Supplementary Oral Anamorelin Mitigates Anorexia and Skeletal Muscle Atrophy Induced by Gemcitabine Plus Cisplatin Systemic Chemotherapy in a Mouse Model

Supplementary Oral Anamorelin Mitigates Anorexia and Skeletal Muscle Atrophy Induced by Gemcitabine Plus Cisplatin Systemic Chemotherapy in a Mouse Model

Chemotherapy-induced adverse effects can reduce the relative dose intensity and quality of life. In this study, we investigated the potential benefit of supplementary anamorelin and 5-aminolevulinic acid (5-ALA) as preventive interventions against a gemcitabine and cisplatin (GC) combination chemoth...

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Bibliographic Details
Main Authors: Makito Miyake, Shunta Hori, Yoshitaka Itami, Yuki Oda, Takuya Owari, Tomomi Fujii, Sayuri Ohnishi, Yosuke Morizawa, Daisuke Gotoh, Yasushi Nakai, Satoshi Anai, Kazumasa Torimoto, Nobumichi Tanaka, Kiyohide Fujimoto
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
chemotherapy
anamorelin
urothelial cancer
bladder neoplasm
appetite loss
muscle atrophy
Online Access:https://www.mdpi.com/2072-6694/12/7/1942

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