Therapeutic efficacy of artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Chad: clinical and genetic surveillance

Therapeutic efficacy of artesunate–amodiaquine and artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Chad: clinical and genetic surveillance

Abstract Background Artesunate–amodiaquine (AS–AQ) and artemether–lumefantrine (AL) are the currently recommended first-and second-line therapies for uncomplicated Plasmodium falciparum infections in Chad. This study assessed the efficacy of these artemisinin-based combinations, proportion of day 3...

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Bibliographic Details
Main Authors: Mahamat Souleymane Issa, Marian Warsame, Moussa Hassane Taisso Mahamat, Issakha Diar Mahamat Saleh, Kodbsse Boulotigam, Honoré Djimrassengar, Ali Haggar Issa, Ousmane Abdelkader, Manah Hassoumi, Mbanga Djimadoum, Cécile Doderer-Lang, Jean Bosco Ndihiokubwayo, Charlotte Rasmussen, Didier Menard
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Malaria Journal
Subjects:
Malaria
Plasmodium falciparum
Artesunate–amodiaquine
Artemether–lumefantrine
Artemisinin resistance
pfKelch13
Online Access:https://doi.org/10.1186/s12936-023-04644-w

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