SARS-CoV-2-on-Chip for Long COVID Management
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a “wicked evil” in this century due to its extended progression and huge human mortalities. Although the diagnosis of SARS-CoV-2 viral infection is made simple and practical by employing reverse transcription polymerase chain re...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-10-01
|
| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/12/10/890 |
| _version_ | 1797474759655555072 |
|---|---|
| author | Jayesh Cherusseri Claire Mary Savio Mohammad Khalid Vishal Chaudhary Arshid Numan Sreekanth J. Varma Amrutha Menon Ajeet Kaushik |
| author_facet | Jayesh Cherusseri Claire Mary Savio Mohammad Khalid Vishal Chaudhary Arshid Numan Sreekanth J. Varma Amrutha Menon Ajeet Kaushik |
| author_sort | Jayesh Cherusseri |
| collection | DOAJ |
| description | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a “wicked evil” in this century due to its extended progression and huge human mortalities. Although the diagnosis of SARS-CoV-2 viral infection is made simple and practical by employing reverse transcription polymerase chain reaction (RT-PCR) investigation, the process is costly, complex, time-consuming, and requires experts for testing and the constraints of a laboratory. Therefore, these challenges have raised the paradigm of on-site portable biosensors on a single chip, which reduces human resources and enables remote access to minimize the overwhelming burden on the existing global healthcare sector. This article reviews the recent advancements in biosensors for long coronavirus disease (COVID) management using a multitude of devices, such as point-of-care biosensors and lab-on-chip biosensors. Furthermore, it details the shift in the paradigm of SARS-CoV-2-on-chip biosensors from the laboratory to on-site detection with intelligent and economical operation, representing near-future diagnostic technologies for public health emergency management. |
| first_indexed | 2024-03-09T20:34:41Z |
| format | Article |
| id | doaj.art-1a878e4cde684c3b9885fcc8310a07ea |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-09T20:34:41Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-1a878e4cde684c3b9885fcc8310a07ea2023-11-23T23:12:18ZengMDPI AGBiosensors2079-63742022-10-01121089010.3390/bios12100890SARS-CoV-2-on-Chip for Long COVID ManagementJayesh Cherusseri0Claire Mary Savio1Mohammad Khalid2Vishal Chaudhary3Arshid Numan4Sreekanth J. Varma5Amrutha Menon6Ajeet Kaushik7Graphene & Advanced 2D Materials Research Group (GAMRG), School of Engineering and Technology, Sunway University, No. 5, Jalan Universiti, Bandar Sunway, Petaling Jaya 47500, MalaysiaDepartment of Engineering, Amity University Dubai, Dubai International Academic City P.O. Box 345019, United Arab EmiratesGraphene & Advanced 2D Materials Research Group (GAMRG), School of Engineering and Technology, Sunway University, No. 5, Jalan Universiti, Bandar Sunway, Petaling Jaya 47500, MalaysiaResearch Cell & Department of Physics, Bhagini Nivedita College, University of Delhi, Delhi 110043, IndiaGraphene & Advanced 2D Materials Research Group (GAMRG), School of Engineering and Technology, Sunway University, No. 5, Jalan Universiti, Bandar Sunway, Petaling Jaya 47500, MalaysiaMaterials for Energy Storage and Optoelectronic Devices Group, Department of Physics, Sanatana Dharma College, University of Kerala, Alappuzha 688003, IndiaAdvanced Bio-Energy Devices Laboratory, Research & Development Division, JC Puli Energy Private Limited, Koduvayur, Palakkad 678501, IndiaNanoBioTech Laboratory, Health System Engineering, Department of Environmental Engineering, Florida Polytechnic University, Lakeland, FL 33805, USASevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a “wicked evil” in this century due to its extended progression and huge human mortalities. Although the diagnosis of SARS-CoV-2 viral infection is made simple and practical by employing reverse transcription polymerase chain reaction (RT-PCR) investigation, the process is costly, complex, time-consuming, and requires experts for testing and the constraints of a laboratory. Therefore, these challenges have raised the paradigm of on-site portable biosensors on a single chip, which reduces human resources and enables remote access to minimize the overwhelming burden on the existing global healthcare sector. This article reviews the recent advancements in biosensors for long coronavirus disease (COVID) management using a multitude of devices, such as point-of-care biosensors and lab-on-chip biosensors. Furthermore, it details the shift in the paradigm of SARS-CoV-2-on-chip biosensors from the laboratory to on-site detection with intelligent and economical operation, representing near-future diagnostic technologies for public health emergency management.https://www.mdpi.com/2079-6374/12/10/890SARS-CoV-2-on-chiplong COVIDRT-PCRpoint-of-carebiosensors |
| spellingShingle | Jayesh Cherusseri Claire Mary Savio Mohammad Khalid Vishal Chaudhary Arshid Numan Sreekanth J. Varma Amrutha Menon Ajeet Kaushik SARS-CoV-2-on-Chip for Long COVID Management Biosensors SARS-CoV-2-on-chip long COVID RT-PCR point-of-care biosensors |
| title | SARS-CoV-2-on-Chip for Long COVID Management |
| title_full | SARS-CoV-2-on-Chip for Long COVID Management |
| title_fullStr | SARS-CoV-2-on-Chip for Long COVID Management |
| title_full_unstemmed | SARS-CoV-2-on-Chip for Long COVID Management |
| title_short | SARS-CoV-2-on-Chip for Long COVID Management |
| title_sort | sars cov 2 on chip for long covid management |
| topic | SARS-CoV-2-on-chip long COVID RT-PCR point-of-care biosensors |
| url | https://www.mdpi.com/2079-6374/12/10/890 |
| work_keys_str_mv | AT jayeshcherusseri sarscov2onchipforlongcovidmanagement AT clairemarysavio sarscov2onchipforlongcovidmanagement AT mohammadkhalid sarscov2onchipforlongcovidmanagement AT vishalchaudhary sarscov2onchipforlongcovidmanagement AT arshidnuman sarscov2onchipforlongcovidmanagement AT sreekanthjvarma sarscov2onchipforlongcovidmanagement AT amruthamenon sarscov2onchipforlongcovidmanagement AT ajeetkaushik sarscov2onchipforlongcovidmanagement |