Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection.

Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection.

Cystic fibrosis is associated with increased inflammatory responses to pathogen challenge. Here we revisited the role of IL-1β in lung pathology using the experimental F508del-CFTR murine model on C57BL/6 genetic background (Cftr(tm1eur) or d/d), on double deficient for d/d and type 1 interleukin-1...

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Main Authors: Jennifer Palomo, Tiffany Marchiol, Julie Piotet, Louis Fauconnier, Marieke Robinet, Flora Reverchon, Marc Le Bert, Dieudonnée Togbe, Ruvalic Buijs-Offerman, Marta Stolarczyk, Valérie F J Quesniaux, Bob J Scholte, Bernhard Ryffel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4264861?pdf=render

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