New Pieces in the Puzzle of uPAR Role in Cell Migration Mechanisms

New Pieces in the Puzzle of uPAR Role in Cell Migration Mechanisms

The urokinase (uPA) receptor (uPAR) plays a key role in cell migration. We previously showed that uPAR-negative HEK-293 cells efficiently migrate toward serum but, after uPAR ectopic expression, migrate only in a uPAR-dependent manner. In fact, migration of uPAR-transfected HEK-293 (uPAR-293) cells...

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Bibliographic Details
Main Authors: Anna Gorrasi, Anna Maria Petrone, Anna Li Santi, Mariaevelina Alfieri, Nunzia Montuori, Pia Ragno
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
urokinase receptor
uPAR
fMLF receptors
FPR1
cell migration
Online Access:https://www.mdpi.com/2073-4409/9/12/2531

Internet

https://www.mdpi.com/2073-4409/9/12/2531

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